Evidence map›Paper›PMID 31696535›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2019

Visual and non-visual properties of filters manipulating short-wavelength light.

Manuel Spitschan, Rafael Lazar, Christian Cajochen

Open access · hybridAbstract read
In one paragraph

Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Manuel SpitschanDepartment of Experimental Psychology, University of Oxford, Oxford, UK.ORCID 0000-0002-8572-9268
Rafael LazarCentre for Chronobiology, Psychiatric Hospital of the University of Basel (UPK), Basel, Switzerland.ORCID 0000-0001-7972-5634
Christian CajochenCentre for Chronobiology, Psychiatric Hospital of the University of Basel (UPK), Basel, Switzerland.ORCID 0000-0003-2699-7171
University of Basel · CH

Funding

Wellcome TrustWellcome Trust 204686/Z/16/Z
6 · The paper itself

Abstract

purposeOptical filters and tints manipulating short-wavelength light (sometimes called 'blue-blocking' or 'blue-attenuating' filters) are used in the management of a range of ocular, retinal, neurological and psychiatric disorders. In many cases, the only available quantification of the optical effects of a given optical filter is the spectral transmittance, which specifies the amount of light transmitted as a function of wavelength.

methodsWe propose a novel physiologically relevant and retinally referenced framework for quantifying the visual and non-visual effects of these filters, incorporating the attenuation of luminance (luminous transmittance), the attenuation of melanopsin activation (melanopsin transmittance), the colour shift, and the reduction of the colour gamut (gamut reduction). Using these criteria, we examined a novel database of spectral transmittance functions of optical filters (n = 121) which were digitally extracted from a variety of sources.

resultsWe find a large diversity in the alteration of visual and non-visual properties. The spectral transmittance properties of the examined filters vary widely, in terms of shapes and cut-off wavelengths. All filters show relatively more melanopsin attenuation than luminance attenuation (lower melanopsin transmittance than luminous transmittance). Across the data set, we find that melanopsin transmittance and luminous transmittance are correlated.

conclusionsWe suggest that future studies and examinations of the physiological effects of optical filters quantify the visual and non-visual effects of the filters beyond the spectral transmittance, which will eventually aid in developing a mechanistic understanding of how different filters affect physiology. We strongly discourage comparing the downstream effects of different filters on, e.g. sleep or circadian responses, without considering their effects on the retinal stimulus.

Indexed as

LightOptics and PhotonicsHumansMelanopsinPhotic StimulationRetinaRod OpsinsVision, OcularMelanopsinRod Opsinsblue-blocking filterscircadianipRGCsopticsshort-wavelength lightsleep

Identifiers

PMID31696535
PMCPMC6887545
OpenAlexW2985244154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.