Evidence map›Paper›PMID 31696505›Full record

ArticleClinical pharmacology and therapeutics2020

Global Pharmacogenomics Within Precision Medicine: Challenges and Opportunities.

Meghan J Chenoweth, Kathleen M Giacomini, Munir Pirmohamed, Susan L Hill, Ron H N van Schaik, Matthias Schwab, Alan R Shuldiner, Mary V Relling, Rachel F Tyndale

Abstract read
In one paragraph

Article in Clinical pharmacology and therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Receptor Pharmacogenomics: Deciphering Genetic Influence on Drug Response.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meghan J ChenowethCampbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Kathleen M GiacominiDepartment of Bioengineering and Therapeutic Sciences, University of California - San Francisco, San Francisco, California, USA.
Munir PirmohamedDepartment of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Susan L HillNational Health Service (NHS), London, UK.
Ron H N van SchaikDepartment of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands.
Matthias SchwabDr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.
Alan R ShuldinerRegeneron Genetics Center, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA.
Mary V RellingPharmaceutical Sciences Department, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Rachel F TyndaleCampbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
CPML - Project 3: Genome-wide Studies of Adverse EffectsP50GM115279 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI RELLING, MARY V · 2015 to 2019
$15.1M
Equipment Supplement for Discovery of Pharmacogenomic Biomarkers for OATP1B1 and OATP1B3R01GM117163 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FLOREZ, JOSE CARLOS, HEDDERSON, MONIQUE MARIE · 2015 to 2023
$5.5M
Clinical Pharmacogenetics Implementation Consortium (CPIC)U24HG010135 · NHGRI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CAUDLE, KELLY E., KLEIN, TERI ELLEN · 2018 to 2022
$5.4M
Glucocorticoids in Lymphoblastic LeukemiaR01CA142665 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI RELLING, MARY V · 2010 to 2020
$4.6M
PGRN Administrative Coordination Hub, ACH (PGRN)U24GM115370 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GIACOMINI, KATHLEEN M, JOHNSON, GRAHAM T. · 2015 to 2019
$2.7M
CIHR FDN-154294Medical Research Council MR/L006758/1NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA142665NHGRI NIH HHS U24 HG010135NIGMS NIH HHS P50 GM115279NIGMS NIH HHS R01 GM117163NIGMS NIH HHS U24 GM115370
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PharmacogeneticsPharmacogenomic VariantsPrecision MedicineBig DataBiomarkers, PharmacologicalCell-Free Nucleic AcidsCost-Benefit AnalysisDatabases, GeneticHumansPharmacogenomic TestingTranslational Research, BiomedicalBiomarkers, PharmacologicalCell-Free Nucleic Acids

Identifiers

PMID31696505
PMCPMC7077926

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.