Evidence map›Paper›PMID 31696236›Full record

ArticleNucleic acids research2020

Mouse Phenome Database: a data repository and analysis suite for curated primary mouse phenotype data.

Molly A Bogue, Vivek M Philip, David O Walton, Stephen C Grubb, Matthew H Dunn, Georgi Kolishovski, Jake Emerson, Gaurab Mukherjee, Timothy Stearns, Hao He and 4 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Hybrids reveal accessible chromatinbioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Methods for Modeling Early Life Stress in Rodents.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
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  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Molly A BogueThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
Vivek M PhilipThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
David O WaltonThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
Stephen C GrubbThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
Matthew H DunnThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
Georgi KolishovskiThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
Jake EmersonThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
Gaurab MukherjeeThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
Timothy StearnsThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
Hao HeThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
Vinita SinhaThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
Beena KadakkuzhaThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
Govindarajan Kunde-RamamoorthyThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.
Elissa J CheslerThe Jackson Laboratory, Bar Harbor, Maine, ME 04609, USA.

Funding

Interventions That Retard Mammalian AgingU01AG022308 · NIA · JACKSON LABORATORY · PI Ronny Korstanje · 2003 to 2026
$30.5M
Mouse Phenome ProjectR01DA028420 · NIDA · JACKSON LABORATORY · PI Elissa J Chesler · 2010 to 2026
$9.5M
Discovery of Addiction-Related Genes with Advanced Mouse ResourcesR01DA037927 · NIDA · JACKSON LABORATORY · PI CHESLER, ELISSA J · 2015 to 2025
$8.1M
Mouse Phenome Database: NIA Interventions Testing Program Data Coordinating CenterU24AG066346 · NIA · JACKSON LABORATORY · PI Elissa J Chesler · 2019 to 2026
$1.7M
CRCNS: Computational Approach to Assess Replicability of Neurobehavior Phenotypes R01DA045401 · NIDA · JACKSON LABORATORY · PI BOGUE, MOLLY A · 2017 to 2019
$760k
NIA NIH HHS U01 AG022308NIA NIH HHS U24 AG066346NIDA NIH HHS R01 DA028420NIDA NIH HHS R01 DA037927NIDA NIH HHS R01 DA045401
6 · The paper itself

Abstract

The Mouse Phenome Database (MPD; https://phenome.jax.org) is a widely accessed and highly functional data repository housing primary phenotype data for the laboratory mouse accessible via APIs and providing tools to analyze and visualize those data. Data come from investigators around the world and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD houses rigorously curated per-animal data with detailed protocols. Public ontologies and controlled vocabularies are used for annotation. In addition to phenotype tools, genetic analysis tools enable users to integrate and interpret genome-phenome relations across the database. Strain types and populations include inbred, recombinant inbred, F1 hybrid, transgenic, targeted mutants, chromosome substitution, Collaborative Cross, Diversity Outbred and other mapping populations. Our new analysis tools allow users to apply selected data in an integrated fashion to address problems in trait associations, reproducibility, polygenic syndrome model selection and multi-trait modeling. As we refine these tools and approaches, we will continue to provide users a means to identify consistent, quality studies that have high translational relevance.

Indexed as

Databases, GeneticGenomePhenomicsPhenotypeAlgorithmsAnimalsComputational BiologyDisease Models, AnimalMiceMice, Inbred StrainsMice, TransgenicMutationProgramming LanguagesSearch EngineSoftwareSpecies Specificity

Identifiers

PMID31696236
PMCPMC7145612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.