Evidence map›Paper›PMID 31696058›Full record

ArticleFrontiers in oncology2019

Cyanidin-3-o-Glucoside Pharmacologically Inhibits Tumorigenesis via Estrogen Receptor β in Melanoma Mice.

Mei Liu, Yaqi Du, Haiwen Li, Li Wang, Donata Ponikwicka-Tyszko, Weronika Lebiedzinska, Agata Pilaszewicz-Puza, Huijiao Liu, Lijun Zhou, Hanlu Fan and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Neurological Effects ofNutrients · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. The Role of Cyanidin-3-Nutrients · 2023
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Recent Advances in Phenolic Metabolites and Skin Cancer.International journal of molecular sciences · 2021
    Review
  15. Review
  16. Article
  17. Cyanidin-3-Food & nutrition research · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

Mei LiuBeijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, China.
Yaqi DuBeijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, China.
Haiwen LiState Key Laboratory of the Agro-Biotechnology, College of Horticultural Science, China Agricultural University, Beijing, China.
Li WangState Key Laboratory of the Agro-Biotechnology, College of Horticultural Science, China Agricultural University, Beijing, China.
Donata Ponikwicka-TyszkoDepartment of Biology and Pathology of Human Reproduction, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland.
Weronika LebiedzinskaDepartment of Reproduction and Gynecological Endocrinology, Medical University of Bialystok, Bialystok, Poland.
Agata Pilaszewicz-PuzaDepartment of Medical Pathomorphology, Medical University of Bialystok, Bialystok, Poland.
Huijiao LiuState Key Laboratory of the Agro-Biotechnology, College of Horticultural Science, China Agricultural University, Beijing, China.
Lijun ZhouBeijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, China.
Hanlu FanBeijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, China.
Mingming WangBeijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, China.
Hua YouState Key Laboratory of the Agro-Biotechnology, College of Horticultural Science, China Agricultural University, Beijing, China.
Slawomir WolczynnskiDepartment of Reproduction and Gynecological Endocrinology, Medical University of Bialystok, Bialystok, Poland.
Nafis RahmanDepartment of Reproduction and Gynecological Endocrinology, Medical University of Bialystok, Bialystok, Poland.
Yang-Dong GuoState Key Laboratory of the Agro-Biotechnology, College of Horticultural Science, China Agricultural University, Beijing, China.
Xiangdong LiBeijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, China.
China Agricultural University · CNMedical University of Białystok · PLChinese PLA General Hospital · CNGuangzhou Medical University · CNInstitute of Animal Reproduction and Food Research · PLUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Expression patterns of estrogen receptors [ERα, ERβ, and G-protein associated ER (GPER)] in melanoma and skin may suggest their differential roles in carcinogenesis. Phytoestrogenic compound cyanidin-3-o-glucoside (C3G) has been shown to inhibit the growth and metastatic potential of melanoma, although the underlying molecular mechanism remains unclear. The aim of this study was to clarify the mechanism of action of C3G in melanoma

Indexed as

apoptosisC3GCCNB1estrogen receptormelanoma

Identifiers

PMID31696058
PMCPMC6817467
OpenAlexW2982226865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.