Evidence map›Paper›PMID 31695961›Full record

ArticleOpen journal of stomatology2019

Periodontitis and Rheumatoid Arthritis in sub-Saharan Africa, gaps and way forward: a systematic review and meta-analysis.

William Buwembo, Ian Guyton Munabi, Mark Kaddumukasa, Haruna Kiryowa, Ethel Nankya, William Evan Johnson, Emmy Okello, Nelson Sewankambo

Abstract read
In one paragraph

Article in Open journal of stomatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Rheumatic diseases in Africa.Nature reviews. Rheumatology · 2021
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

William BuwemboDepartment of Human Anatomy, School of Biomedical Sciences, Makerere University College of Health Sciences, Kampala Uganda.
Ian Guyton MunabiDepartment of Human Anatomy, School of Biomedical Sciences, Makerere University College of Health Sciences, Kampala Uganda.
Mark KaddumukasaDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, Kampala Uganda.
Haruna KiryowaDepartment of Human Anatomy, School of Biomedical Sciences, Makerere University College of Health Sciences, Kampala Uganda.
Ethel NankyaDivision of Computational Biomedicine, Boston University School of Medicine, Boston, MA, Boston University, USA.
William Evan JohnsonDivision of Computational Biomedicine, Boston University School of Medicine, Boston, MA, Boston University, USA.
Emmy OkelloDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, Kampala Uganda.
Nelson SewankamboDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, Kampala Uganda.

Funding

NURTURE:Research Training and Mentoring Program for Career Development of Faculty at Makerere University College of Health SciencesD43TW010132 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI SEWANKAMBO, NELSON K · 2015 to 2019
$4.3M
FIC NIH HHS D43 TW010132
6 · The paper itself

Abstract

backgroundThis review identified papers that described periodontitis and rheumatoid arthritis in sub-Saharan Africa. Only English language publications from January 2010 to December 2017 describing original research in sub-Saharan Africa on the association between periodontitis and rheumatoid arthritis were considered for this study.

methodsPublished databases: PubMed, Science direct and Google scholar, were searched using terms "periodontitis", "rheumatoid arthritis" and "Sub-Saharan Africa" to generate a set of putative studies. Articles with data on both rheumatoid arthritis and periodontitis compared to controls were selected. Studies on the association of periodontitis with cardiovascular disease, arthritis or rheumatoid arthritis alone were excluded. Data were extracted, critically appraised, and analyzed using a random-effect Mantel-Haenszel meta-analysis on plaque index, gingival index, pocket depth and clinical attachment loss.

resultsThree publications were selected for the systematic review and 2 for the meta-analysis. Two studies were from Sudan, and one was from Burina Faso. There was a significant increase in pocket depth (mean difference: 0.31; 95% CI: 0.21, 0.41; N= 274; (p ≤ 0.001) and clinical attachment loss (mean difference: 0.47; 95% CI: 0.22, 0.75; N= 274; (p ≤ 0.001) in participants with rheumatoid arthritis compared to normal controls.

conclusionFindings from these combined studies show a significant relationship between periodontal disease and rheumatoid arthritis with increased periodontal pocket depth and clinical attachment loss. They also highlight the need for additional work especially in the area of associating rheumatoid arthritis with

Indexed as

PeriodontitisRheumatoid arthritissub-Saharan Africa

Identifiers

PMID31695961
PMCPMC6834353

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.