Evidence map›Paper›PMID 31695923›Full record

ArticleCanadian journal of kidney health and disease2019

Long-Term Impact of Bariatric Surgery on Renal Outcomes at a Community-Based Publicly Funded Bariatric Program: The Regina Bariatric Study.

Mark McIsaac, Gordon Kaban, Adam Clay, Warren Berry, Bhanu Prasad

Open access · goldAbstract read
In one paragraph

Article in Canadian journal of kidney health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mark McIsaacUniversity of Saskatchewan College of Medicine, Saskatoon, Canada.
Gordon KabanRegina General Hospital, SK, Canada.
Adam ClaySaskatchewan Health Authority, Regina, Canada.
Warren BerrySaskatchewan Health Authority, Regina, Canada.
Bhanu PrasadRegina General Hospital, SK, Canada.ORCID https://orcid.org/0000-0002-1139-4821
Regina General Hospital · CASaskatchewan Health Authority · CAUniversity of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is recognized as an independent risk factor for chronic kidney disease through multiple direct and indirect biological pathways. Bariatric surgery is a proven, effective method for sustained weight loss. However, there is a relative paucity of data on the impact of bariatric surgery on renal outcomes.

objectiveThe primary objective was to evaluate the change in urine albumin/creatinine ratio (ACR) in patients undergoing bariatric surgery, at 12 months after the procedure. Secondary objectives were to determine the changes in ACR at (6 and 24 months), estimated glomerular filtration rate (eGFR; 6, 12, and 24 months), and hemoglobin A1c (HbA1c); 12 and 24 months) after the procedure.

designThis observational retrospective cohort study included consecutive obese patients who underwent bariatric surgery.

settingProvincial Bariatric Surgery Clinic at the Regina General Hospital, Saskatchewan. PATIENTS: This study includes 471 consecutive obese adult patients who underwent bariatric surgery between 2008 and 2015. MEASUREMENTS: We studied the impact of bariatric surgery on body mass index (BMI), renal outcomes (urine ACR and eGFR) and metabolic outcomes (fasting glucose, total cholesterol, low-density lipoprotein, triglycerides, and HbA1c) in 471 patients.

methodsPatients were followed for 2 years postsurgery in the bariatric clinic. Mixed linear models that accounted for the repeated nature of the data were used to access changes in outcomes over time.

resultsPatients were predominantly female (81%) with a mean age (±SD) of 46 ± 10 years. Most patients (87%) had a BMI > 40 kg/m LIMITATIONS: This was a retrospective chart review, with the lack of a control group. Patients with eGFR less than 60 mL/min/1.73 m

conclusionsOur results suggest bariatric surgery significantly decreased weight and consequently improved renal and metabolic outcomes (eGFR, ACR, fasting glucose, cholesterol, and triglycerides) in patients with elevated BMI.

Indexed as

albuminuriabariatric surgeryglomerular filtration rateobesityrenal outcomesurine albumin/creatinine ratio

Identifiers

PMID31695923
PMCPMC6820179
OpenAlexW2981813310

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.