ArticleTheranostics2019
The hepatocyte-specifically expressed lnc-HSER alleviates hepatic fibrosis by inhibiting hepatocyte apoptosis and epithelial-mesenchymal transition.
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Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
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29 citing papers in PubMed, 54 citations in OpenAlex.
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- GPR56 function as a key repressor in hepatocyte pyroptosis and the pathogenesis of liver fibrosis.Journal of translational medicine · 2025Article
- MEOX1-mediated transcriptional regulation of circABHD3 exacerbates hepatic fibrosis through promoting m6A/YTHDF2-dependent YPEL3 mRNA decay to activate β-catenin signaling.PLoS genetics · 2025Article
- Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.Hepatic medicine : evidence and research · 2025Article
- Role of Ubiquitin-regulated EMT in Cancer Metastasis and Chemoresistance.International journal of biological sciences · 2025Review
- [Inhibiting Yes-associated protein alleviates CClNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- Application of the Human Amniotic Membrane as an Adjuvant Therapy for the Treatment of Hepatocellular Carcinoma.Advances in experimental medicine and biology · 2024Review
- Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways.Military Medical Research · 2023Article
- LncRNA-Gm9866 promotes liver fibrosis by activating TGFβ/Smad signaling via targeting Fam98b.Journal of translational medicine · 2023Article
- lncRNA Helf promotes hepatic inflammation and fibrosis by interacting with PTBP1 to facilitate PIK3R5 mRNA stabilization.Cellular & molecular biology letters · 2023Article
- Long non‑coding RNA PTCSC3 suppresses triple‑negative breast cancer by downregulating long non‑coding RNA MIR100HG.Oncology letters · 2023Article
- Tcf21 Alleviates Pancreatic Fibrosis by Regulating the Epithelial-Mesenchymal Transformation of Pancreatic Stellate Cells.Digestive diseases and sciences · 2023Article
- Alterations of long noncoding RNAs and mRNAs in extracellular vesicles derived from the murine heart post-ischemia-reperfusion injury.Journal of cellular and molecular medicine · 2022Article
- Lnc Tmem235 promotes repair of early steroid-induced osteonecrosis of the femoral head by inhibiting hypoxia-induced apoptosis of BMSCs.Experimental & molecular medicine · 2022Article
- LncRNA Airn maintains LSEC differentiation to alleviate liver fibrosis via the KLF2-eNOS-sGC pathway.BMC medicine · 2022Article
- BMP4 and Gremlin 1 regulate hepatic cell senescence during clinical progression of NAFLD/NASH.Nature metabolism · 2022Article
- Long noncoding RNA KCNQ1OT1 inhibits osteoclast differentiation by regulating the miR-128-3p/NFAT5 axis.Aging · 2022Article
- Silencing of LncRNA KCNQ1OT1 confers an inhibitory effect on renal fibrosis through repressing miR-124-3p activity.Bioengineered · 2022Article
- The single nucleotide polymorphism rs1814521 in long non-coding RNA ADGRG3 associates with the susceptibility to silicosis: a multi-stage study.Environmental health and preventive medicine · 2022Article
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Authors and funding
16 authors at 2 institutions in 1 country.
Kun ZhangDepartment of Histology and Embryology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Mengxia ZhangDepartment of Histology and Embryology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Qingbin YaoDepartment of Histology and Embryology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Xiaohui HanDepartment of Histology and Embryology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Yanmian ZhaoDepartment of Histology and Embryology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Lina ZhengDepartment of Histology and Embryology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Guantong LiThe Third Central Clinical College of Tianjin Medical University, Department of Hepatology and Gastroenterology, Tianjin Third Central Hospital, Tianjin Key Laboratory of Artificial Cells, Artificial Cell Engineering Technology Research Center of Public Health Ministry, Tianjin, China.
Qi LiuDepartment of Histology and Embryology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Yanan ChangDepartment of Pathology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Peijun ZhangTianjin Central Hospital of Gynecology Obstetrics, Tianjin, China.
Hongmei CuiDepartment of Histology and Embryology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Zhemin ShiDepartment of Histology and Embryology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Ting ChenDepartment of Histology and Embryology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Zhi YaoDepartment of Immunology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Tao HanThe Third Central Clinical College of Tianjin Medical University, Department of Hepatology and Gastroenterology, Tianjin Third Central Hospital, Tianjin Key Laboratory of Artificial Cells, Artificial Cell Engineering Technology Research Center of Public Health Ministry, Tianjin, China.
Wei HongDepartment of Histology and Embryology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Tianjin Medical University · CNTianjin Central Hospital of Gynecology Obstetrics · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
Liver fibrosis leading to cirrhosis is one of the major health burdens worldwide with currently limited therapeutic options available. Long noncoding RNAs (lncRNAs) play important roles in various biological and pathological processes in a cell- or tissue-specific manner. However, there is still an important gap in the understanding of the role of hepatocyte-specific lncRNAs in liver fibrosis.
Indexed as
AnimalsApoptosisCells, CulturedEpithelial-Mesenchymal TransitionHepatic Stellate CellsHepatocytesHumansLiverLiver CirrhosisMiceMice, Inbred BALB CRNA, Long NoncodingSignal TransductionRNA, Long NoncodingC5AR1hepatocyteliver fibrosislncRNANotch
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.