Evidence map›Paper›PMID 31695700›Full record

ArticleFrontiers in immunology2019

NKT-Like (CD3+CD56+) Cells in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors.

Jani-Sofia Almeida, Patrícia Couceiro, Nelson López-Sejas, Vera Alves, Lenka Růžičková, Raquel Tarazona, Rafael Solana, Paulo Freitas-Tavares, Manuel Santos-Rosa, Paulo Rodrigues-Santos

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
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  7. Immune Profile in COVID-19: Unveiling TInternational journal of molecular sciences · 2024
    Article
  8. Article
  9. Review
  10. Regulatory TCells · 2023
    Review
  11. Article
  12. Article
  13. Natural Killer T-like Cells: Immunobiology and Role in Disease.International journal of molecular sciences · 2023
    Review
  14. Article
  15. Review
  16. Dysfunction of circulating CD3International journal of medical sciences · 2023
    Article
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Jani-Sofia AlmeidaFaculty of Medicine (FMUC), Institute of Immunology, University of Coimbra, Coimbra, Portugal.
Patrícia CouceiroLaboratory of Immunology and Oncology, Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.
Nelson López-SejasDepartment of Immunology, IMIBIC - Reina Sofia University Hospital, University of Cordoba, Córdoba, Spain.
Vera AlvesFaculty of Medicine (FMUC), Institute of Immunology, University of Coimbra, Coimbra, Portugal.
Lenka RůžičkováHematology Service, Coimbra Hospital and Universitary Centre (CHUC), Coimbra, Portugal.
Raquel TarazonaImmunology Unit, University of Extremadura, Cáceres, Spain.
Rafael SolanaDepartment of Immunology, IMIBIC - Reina Sofia University Hospital, University of Cordoba, Córdoba, Spain.
Paulo Freitas-TavaresHematology Service, Coimbra Hospital and Universitary Centre (CHUC), Coimbra, Portugal.
Manuel Santos-RosaFaculty of Medicine (FMUC), Institute of Immunology, University of Coimbra, Coimbra, Portugal.
Paulo Rodrigues-SantosFaculty of Medicine (FMUC), Institute of Immunology, University of Coimbra, Coimbra, Portugal.
University of Coimbra · PTHospitais da Universidade de Coimbra · PTInstituto Maimónides de Investigación Biomédica de Córdoba · ESUniversidad de Extremadura · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapy with Tyrosine Kinase Inhibitors (TKI) aiming stable deep molecular response is the gold standard to treat Chronic Myeloid Leukemia (CML). NKT-like cells (CD3

Indexed as

Antigens, DifferentiationFemaleGene Expression Regulation, LeukemicHumansK562 CellsLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMaleNatural Killer T-CellsNeoplasm ProteinsProtein Kinase InhibitorsAntigens, DifferentiationNeoplasm ProteinsProtein Kinase Inhibitorschronic myeloid leukemiaimmune checkpointsnatural cytotoxicity receptorsNKT-like cellstyrosine kinase inhibitors

Identifiers

PMID31695700
PMCPMC6817724
OpenAlexW2982218867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.