Evidence map›Paper›PMID 31695695›Full record

SynthesisFrontiers in immunology2019

Anti-p200 Pemphigoid: A Systematic Review.

Khalaf Kridin, A Razzaque Ahmed

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Incidence of P200 pemphigoid: A nationwide study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. [Pemphigoid diseases in older adults].Dermatologie (Heidelberg, Germany) · 2023
    Review
  13. Article
  14. Review
  15. Review
  16. [Rare variants of pemphigoid diseases].Dermatologie (Heidelberg, Germany) · 2022
    Review
  17. Management of Coexisting Bullous Pemphigoid and Psoriasis: A Review.American journal of clinical dermatology · 2022
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Khalaf KridinDepartment of Dermatology, Rambam Health Care Campus, Haifa, Israel.
A Razzaque AhmedDepartment of Dermatology, Center for Blistering Diseases, Tufts University School of Medicine, Boston, MA, United States.
Rambam Health Care Campus · ILTufts University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The many clinical aspects of anti-p200 pemphigoid are not well-characterized. We aimed to analyze and correlate known existing data on the epidemiological, clinical, histological, and immunological features of anti-p200 pemphigoid. We performed a review using Medline, Embase, and Web of Science databases (1900-2018). Case reports and series of patients were included. A total of 68 eligible studies that comprised 113 anti-p200 pemphigoid patients were included in the qualitative analysis, where there was a mean age of onset of 65.5 years. All patients presented with bullae/vesicles, and 54.3% had urticarial plaques. A similarity to bullous pemphigoid was reported in 66.1% of cases, but palmoplantar (51.4%), cephalic (40.3%), and mucosal (38.5%) involvement, besides frequent development of scars/milia (15.7%), were reported. Autoantibodies against recombinant laminin γ1 were detected in the sera of 73.1% of patients. Psoriasis was present in 28.3% of anti-p200 pemphigoid patients, particularly among Japanese patients (56.4%). The incidence of pustular psoriasis in this subgroup, was significantly greater than in the normal population. In conclusion, the diagnosis of anti-p200 pemphigoid may be suspected when a subepidermal autoimmune blistering disease develops in a younger age group, along with significant acral and cephalic distribution and mucosal involvement.

Indexed as

Pemphigoid, BullousPsoriasisAgedAge of OnsetAutoantibodiesFemaleHumansLamininMaleAutoantibodiesLamininlaminin gamma 1anti-laminin gamma-1 pemphigoidanti-p200 pemphigoidBMZ autoantibodiesELISAIIF of salt-split skinimmunoblottingmucosal diseasepsoriasis

Identifiers

PMID31695695
PMCPMC6817563
OpenAlexW2981563239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.