ReviewOrthopedic research and reviews2019
Spinal Aneurysmal Bone Cysts (ABCs): Optimal Management.
Review in Orthopedic research and reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Spinal aneurysmal bone cysts in children - institutional chart review and recommendation for treatment.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- The best solution is the simplest: advances in surgical and minimally invasive management of aneurysmal and simple bone cysts.Journal of orthopaedic surgery and research · 2026Review
- Resection and 3D-printed prosthetic reconstruction of a giant aneurysmal bone cyst in the atlas: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Exploring Aneurysmal Bone Cysts of the Skull: Insights from a Review of the Literature and a Case Report.Children (Basel, Switzerland) · 2025Review
- Percutaneous Doxycycline Ablation for Recurrent Aneurysmal Bone Cyst in the Sacroiliac Joint: A Case Report.Journal of orthopaedic case reports · 2024Article
- Modern treatment of unicameral and aneurysmatic bone cysts.EFORT open reviews · 2024Review
- Tumors of the Posterior Elements of the Spine in Children-an Overview.Indian journal of surgical oncology · 2024Review
- Surgical management of pediatric spinal aneurysmal bone cysts: patient series.Journal of neurosurgery. Case lessons · 2024Article
- Management of aggressive recurrent thoracic spine aneurysmal bone cyst in a 7-year-old male: A case report and review of the literature.Surgical neurology international · 2024Article
- Spinal tumours: recommendations of the Polish Society of Spine Surgery, the Polish Society of Oncology, the Polish Society of Neurosurgeons, the Polish Society of Oncologic Surgery, the Polish Society of Oncologic Radiotherapy, and the Polish Society of Orthopaedics and Traumatology.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Doxycycline sclerotherapy of cervical spine aneurysmal bone cysts: single-institution 13-year experience.Pediatric radiology · 2022Article
- Topical hemostatic agents in neurosurgery, a comprehensive review: 15 years update.Neurosurgical review · 2022Review
- The role of percutaneous transarterial embolization in the management of spinal bone tumors: a literature review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Review
- Imaging features of Vertebral Aneurysmal Bone Cyst and the clinical value of interventional embolization.Experimental and therapeutic medicine · 2020Article
- Spondylectomy in the treatment of neoplastic spinal lesions - A retrospective outcome analysis of 582 patients using a patient-level meta-analysis.Journal of craniovertebral junction & spineReview
- Bony lesions of cranium and spine: A study of 123 cases.Journal of craniovertebral junction & spineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo review the published literature on the treatment of aneurysmal bone cysts (ABCs).
methodA systematic review of the English literature to April 2019 for all articles, with a minimum of three patients and 2-year follow-up, reporting on the treatment of spinal ABCs. The various treatment options were compared for the rates of recurrence, complications and mortality.
resultsTwenty-one articles and 272 patients (mean age 16.9 years, range 3-67) were included in this review. The overall recurrence rate for ABCs following all treatments is 12.8%. This is highest in those lesions described as being treated with isolated surgiflo injection into the lesion (100%), decompression/laminectomy (42.3%), partial excision/resection (35.7%) and curettage alone (25.0%). Radiotherapy alone or in conjunction with operative intervention offers excellent cure rates. Adjuncts to operative intervention, including cryotherapy or phenol reduce the recurrence rates, whereas embolization does not. The most common complications are persistent neurological deficits, spinal deformity, and continued pain. The overall mortality rates are low (1.5%). The reoperation rates are higher in surgical than non-surgical treatments and most are performed for progressive deformity. DISCUSSION: ABCs are highly radiosensitive. However, with the unknown longer-term risk of radiotherapy, surgical treatments, ideally with complete resection, and the use of adjunctive therapies such as cryotherapy or phenol, offer the best chance of cure. SAE is a useful adjunct to reduce intraoperative bleeding, but this study suggests that it only modestly improves recurrence rates. Newer techniques including bisphosphonate and doxycycline administration offer potential benefits, but their efficacy requires further investigation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.