Evidence map›Paper›PMID 31695475›Full record

ArticleInternational journal of general medicine2019

A Unique Case Of Tenofovir-Induced DRESS Syndrome Associated With Raynaud's Of The Tongue.

Obadah Aqtash, Aman Naim Ajmeri, Brent A Thornhill, Elise Anderson, Ryan Carroll, Adee Elhamdani, Eva Tackett

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of general medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Obadah AqtashInternal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25701, USA.
Aman Naim AjmeriInternal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25701, USA.ORCID 0000-0003-3145-4403
Brent A ThornhillInternal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25701, USA.
Elise AndersonCharleston Area Medical Center, Charelston, WV 25701, USA.
Ryan CarrollInternal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25701, USA.
Adee ElhamdaniInternal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25701, USA.ORCID 0000-0002-7065-841X
Eva TackettInternal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25701, USA.
Marshall University · USCharleston Area Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a potentially fatal severe adverse reaction to medications. Numerous drugs have been implicated, with carbamazepine and allopurinol being the most common. Tenofovir-induced DRESS is extremely rare. We report a case of a 65-year-old male patient with a diffuse exfoliative maculopapular rash across his entire body of five weeks of duration. The patient also had icteric sclera, abnormal liver enzymes and Raynaud's of the tongue, nose and the left fifth finger. After discontinuation of tenofovir, the case resolved over a span of ten days. A high index of suspicion is crucial along with the prompt withdrawal of the offending medication for a good outcome.

Indexed as

DRESSdrug reaction with eosinophilia and systemic symptomsRaynaud’s of the tongueRaynaud’s phenomenatenofovirtenofovir-induced DRESS

Identifiers

PMID31695475
PMCPMC6815911
OpenAlexW2981643852

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.