Evidence map›Paper›PMID 31695444›Full record

ArticleInfection and drug resistance2019

Time series analysis of antibacterial usage and bacterial resistance in China: observations from a tertiary hospital from 2014 to 2018.

Shuangshuang Zeng, Zhijie Xu, Xiang Wang, Wanli Liu, Long Qian, Xi Chen, Jie Wei, Minwen Zhu, Zhicheng Gong, Yuanliang Yan

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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  14. Antimicrobial Resistance in ClinicalAntimicrobial agents and chemotherapy · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shuangshuang Zeng *Department of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People's Republic of China.
Zhijie Xu *Department of Pathology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People's Republic of China.
Xiang WangDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People's Republic of China.
Wanli LiuDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People's Republic of China.
Long QianDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People's Republic of China.
Xi ChenDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People's Republic of China.
Jie WeiDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People's Republic of China.
Minwen ZhuDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People's Republic of China.
Zhicheng GongDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People's Republic of China.
Yuanliang YanDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People's Republic of China.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe trends and correlation between antibacterial exposure and bacterial resistance from hospitalized patients in a hospital in southern China. PATIENTS AND

methodsThis study used hospital-wide data regarding antimicrobial resistance and consumption between January 1, 2014 and December 31, 2018. Antibacterial consumption was expressed as antimicrobial use density (AUD). The changes in trends and associations between antibacterial utilization and resistance were analyzed using linear regression and time series analysis.

resultsThe total AUD of all antimicrobials decreased year by year (50.66 in 2014 vs 44.28 in 2018,

conclusionThe consumption of antibiotics and antibiotic resistance has been significantly improved in this tertiary hospital. Additionally, the efforts of China's antibiotic management may be suggested by the relationship between indicated antibiotic resistance and consumption. However, overall AUD levels and poor control of the use of antibiotics, such as quinolones and tetracyclines, still require strengthened management.

Indexed as

antibacterial usagebacterial resistanceChinatime series analysis

Identifiers

PMID31695444
PMCPMC6717838
OpenAlexW2970302304

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.