Evidence map›Paper›PMID 31695442›Full record

ArticleInfection and drug resistance2019

Development, optimization, and validation of an in-house Dot-ELISA rapid test based on SAG1 and GRA7 proteins for serological detection of

Aref Teimouri, Mohammad Hossein Modarressi, Saeedeh Shojaee, Mehdi Mohebali, Mostafa Rezaian, Hossein Keshavarz

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Aref TeimouriDepartment of Medical Parasitology and Mycology, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Hossein ModarressiDepartment of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Saeedeh ShojaeeDepartment of Medical Parasitology and Mycology, Tehran University of Medical Sciences, Tehran, Iran.
Mehdi MohebaliDepartment of Medical Parasitology and Mycology, Tehran University of Medical Sciences, Tehran, Iran.
Mostafa RezaianDepartment of Medical Parasitology and Mycology, Tehran University of Medical Sciences, Tehran, Iran.
Hossein KeshavarzDepartment of Medical Parasitology and Mycology, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the present study was to develop a simple, portable, and rapid assay for serodiagnosis of toxoplasmosis based on recombinant

methodsThe rSAG1 and rGRA7 proteins were expressed in

resultsResults from the comparison of in-house rSAG1-Dot-ELISA with ELISA for the detection of anti-

conclusionThe highlighted parameters of combined recombinant proteins were more significant than those of single recombinant proteins in in-house Dot-ELISA. These data suggest that the in-house Dot-ELISA based on rSAG1 and rGRA7 combination is a promising diagnostic tool with a similar sensitivity to the native antigens of

Indexed as

in-house Dot-ELISArecombinant proteinsrGRA7rSAG1soluble tachyzoite antigen (STAg)Toxoplasma gondii RH strain

Identifiers

PMID31695442
PMCPMC6717716
OpenAlexW2970068601

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.