ArticleOncoTargets and therapy2019
An immune-related gene pairs signature predicts overall survival in serous ovarian carcinoma.
Article in OncoTargets and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Identification of a novel immune-related gene signature for prognosis and the tumor microenvironment in patients with uveal melanoma combining single-cell and bulk sequencing data.Frontiers in immunology · 2023Article
- Identification of an Individualized Prognostic Biomarker for Serous Ovarian Cancer: A Qualitative Model.Diagnostics (Basel, Switzerland) · 2022Article
- Identification of an immune-related gene pair signature in breast cancer.Translational cancer research · 2022Article
- Review
- Immune Subtype Profiling and Establishment of Prognostic Immune-Related lncRNA Pairs in Human Ovarian Cancer.Computational and mathematical methods in medicine · 2022Article
- A 25 Immune-Related Gene Pair Signature Predicts Overall Survival in Cervical Cancer.Cancer informatics · 2022Article
- Insulin-like growth factor 2 receptor is a key immune-related gene that is correlated with a poor prognosis in patients with triple-negative breast cancer: A bioinformatics analysis.Frontiers in oncology · 2022Article
- Prediction of clinical prognosis in cutaneous melanoma using an immune-related gene pair signature.Bioengineered · 2021Article
- Individualized prognostic signature for pancreatic carcinoma validated by integrating immune-related gene pairs (IRGPs).Bioengineered · 2021Article
- Development and validation of a hypoxia-related gene pair signature to predict overall survival in head and neck squamous cell carcinoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021Article
- Development of immune gene pair-based signature predictive of prognosis and immunotherapy in esophageal cancer.Annals of translational medicine · 2021Article
- A novel immune-related gene pair prognostic signature for predicting overall survival in bladder cancer.BMC cancer · 2021Article
- Epithelial-to-Mesenchymal Transition in the Light of Plasticity and Hybrid E/M States.Journal of clinical medicine · 2021Review
- Identification and validation of a risk signature based on extracellular matrix-related genes in gliomas.Medicine · 2021Article
- Development of an immune-related gene pairs signature for predicting clinical outcome in lung adenocarcinoma.Scientific reports · 2021Article
- An Immune-Related Gene Pairs Signature for Predicting Survival in Glioblastoma.Frontiers in oncology · 2021Article
- Development and Validation of an Immune-Related Gene Pairs Signature in Grade II/III Glioma.International journal of general medicine · 2021Article
- Predicting the Survival and Immune Landscape of Colorectal Cancer Patients Using an Immune-Related lncRNA Pair Model.Frontiers in genetics · 2021Article
- Identification of Immune-Related LncRNA Pairs for Predicting Prognosis and Immunotherapeutic Response in Head and Neck Squamous Cell Carcinoma.Frontiers in immunology · 2021Article
- Predicting the clinical outcome of melanoma using an immune-related gene pairs signature.PloS one · 2020Article
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Authors and funding
10 authors.
Funding
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Abstract
backgroundOvarian cancer has the highest death rate of all fatal gynecological cancers. Increasing evidence has depicted the correlation between serous ovarian carcinoma prognosis and immune signature. Therefore, the aim of this study is to develop a robust prognostic immune-related gene pairs (IRGPs) signature for estimating overall survival (OS) of HGSOC.
methodsGene expression profiling and clinical information of serous ovarian carcinoma patients were derived from three public data sets, divided into training and validation cohorts. Immune genes significantly associated with prognosis were selected.
resultsAmong 1,534 immune genes, a 20 IRGPs signature was built which was significantly associated with OS in the training cohort (
conclusionWe successfully constructed a robust IRGPs signature with prognostic values for serous ovarian carcinoma, providing new insights into post-operational treatment strategies.
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