Evidence map›Paper›PMID 31695369›Full record

ArticleInternational journal of nanomedicine2019

Cerium oxide NPs mitigate the amyloid formation of α-synuclein and associated cytotoxicity.

Zahra Zand, Pegah Afarinesh Khaki, Abbas Salihi, Majid Sharifi, Nadir Mustafa Qadir Nanakali, Asaad Ab Alasady, Falah Mohammad Aziz, Koorosh Shahpasand, Anwarul Hasan, Mojtaba Falahati

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
  2. Review
  3. Ceria nanoparticles: biomedical applications and toxicity.Journal of Zhejiang University. Science. B · 2024
    Review
  4. Review
  5. Review
  6. Article
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  9. Article
  10. Review
  11. Review
  12. Inhibition of Amyloid Aggregation and Toxicity with Janus Iron Oxide Nanoparticles.Chemistry of materials : a publication of the American Chemical Society · 2021
    Article
  13. Article
  14. Emerging Nanotechnology for Treatment of Alzheimer's and Parkinson's Disease.Frontiers in bioengineering and biotechnology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Zahra Zand *Department of Biochemistry and Biophysics, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Pegah Afarinesh Khaki *Department of Molecular Genetics, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Abbas SalihiDepartment of Biology, College of Science, Salahaddin University-Erbil, Kurdistan Region, Iraq.
Majid SharifiDepartment of Nanomedicine, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Nadir Mustafa Qadir NanakaliDepartment of Biology, College of Science, Cihan University-Erbil, Kurdistan Region, Iraq.
Asaad Ab AlasadyAnatomy, Biology and Histology Unit, College of Medicine, University of Duhok, Kurdistan Region, Iraq.
Falah Mohammad AzizDepartment of Biology, College of Science, Salahaddin University-Erbil, Kurdistan Region, Iraq.
Koorosh ShahpasandDepartment of Brain and Cognitive Sciences, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
Anwarul HasanDepartment of Mechanical and Industrial Engineering, College of Engineering, Qatar University, Doha 2713, Qatar.
Mojtaba FalahatiDepartment of Nanomedicine, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Islamic Azad University Medical Branch of Tehran · IRSalahaddin University-Erbil · IQCihan University-Erbil · IQQatar University · QARoyan Institute · IRUniversity of Duhok · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimAmong therapeutic proposals for amyloid-associated disorders, special attention has been given to the exploitation of nanoparticles (NPs) as promising agents against aggregation.

methodsIn this paper, the inhibitory effect of cerium oxide (CeO

resultsThT and ANS fluorescence assays indicated that CeO

conclusionIt may be concluded that CeO

Indexed as

alpha-SynucleinAmyloidApoptosisbcl-2-Associated X ProteinBenzothiazolesCell Line, TumorCeriumCongo RedHumansKineticsMolecular Docking SimulationMolecular Dynamics SimulationNanoparticlesNecrosisRNA, MessengerSpectrometry, Fluorescencealpha-SynucleinAmyloidbcl-2-Associated X ProteinBenzothiazolesceric oxideCeriumCongo RedRNA, Messengerthioflavin Tamyloidcellular assaycerium oxidecytotoxicityinhibitionnanoparticlespectroscopy

Identifiers

PMID31695369
PMCPMC6718255
OpenAlexW2970144768

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.