ArticleClinical interventions in aging2019
Medication Regimen Complexity In 8 Australian Residential Aged Care Facilities: Impact Of Age, Length Of Stay, Comorbidity, Frailty, And Dependence In Activities Of Daily Living.
Article in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The FRAIL-NH Scale: Systematic Review of the Use, Validity and Adaptations for Frailty Screening in Nursing Homes.The journal of nutrition, health & aging · 2021Pooled it
- Process Evaluation of the SImplification of Medications Prescribed to Long-tErm Care Residents (SIMPLER) Cluster Randomized Controlled Trial: A Mixed Methods Study.International journal of environmental research and public health · 2021Trial
- Identification of Training Needs and Development of a Work-Integrated Training Program for Aged Care On-Site Pharmacists: Protocol for a Co-Design Study.JMIR research protocols · 2026Article
- Global Trends and Research Hot Spots in Medication Regimen Simplification: Bibliometric Analysis.JMIR aging · 2026Article
- Nurse Practitioner-Pharmacist Collaboration for Medication Regimen Simplification: Pilot and Feasibility Study of a New Telehealth Model of Care.Journal of nursing management · 2026Article
- Polypharmacy appropriateness in Italian Long-Term Care Facilities: the nationwide prescription day point survey.Aging clinical and experimental research · 2025Article
- The effect of commonly used non-antibiotic medications on antimicrobial resistance development in Escherichia coli.npj antimicrobials and resistance · 2025Article
- Article
- Statement on medication simplification in long-term care facilities by the Japanese Society of Geriatric Pharmacy: English translation of the Japanese article.Geriatrics & gerontology international · 2025Review
- Development and validation of a clinical score to identify hospitalised patients at high risk of drug-related problems.Journal of pharmaceutical policy and practice · 2025Article
- Managing falls onsite in residential aged care homes reduced hospitalisation: Mixed methods results from the Falls Outreach and Residential Mobile Assessment Team (FORMAT) pilot study.Australasian journal on ageing · 2024Article
- Longitudinal cohort study of discrepancies between prescribed and administered polypharmacy rates: implications for National Aged Care Quality Indicator Programs.BMJ quality & safety · 2024Article
- Potentially Inappropriate Medication: A Pilot Study in Institutionalized Older Adults.Healthcare (Basel, Switzerland) · 2024Article
- Medication Management Through Collaborative Practice for Children With Medical Complexity: A Prospective Case Series.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024Article
- The prevalence and perceived effectiveness of using a medication-swallowing lubricant in aged care facilities across Australia.Aging medicine (Milton (N.S.W)) · 2023Article
- Medication Regimen Complexity Index Score at Admission as a Predictor of Inpatient Outcomes: A Machine Learning Approach.International journal of environmental research and public health · 2023Article
- Medication regimen complexity index and rehabilitation outcomes in post-acute hip fracture patients study: a retrospective study.International journal of clinical pharmacy · 2022Article
- Potentially inappropriate medications in relation to length of nursing home stay among older adults.BMC geriatrics · 2022Article
- Methodological Challenges for Epidemiologic Studies of Deprescribing at the End of Life.Current epidemiology reports · 2021Article
- Impact of Medication Regimen Simplification on Medication Incidents in Residential Aged Care: SIMPLER Randomized Controlled Trial.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore variation in medication regimen complexity in residential aged care facilities (RACFs) according to resident age, length of stay, comorbidity, dementia severity, frailty, and dependence in activities of daily living (ADLs), and compare number of daily administration times and Medication Regimen Complexity Index (MRCI) as measures of regimen complexity.
methodsThis study was a cross-sectional analysis of baseline data from the SImplification of Medications Prescribed to Long-tErm care Residents (SIMPLER) cluster-randomized controlled trial. The SIMPLER study recruited 242 residents with at least one medication charted for regular administration from 8 RACFs in South Australia. Comorbidity was assessed using the Charlson Comorbidity Index (CCI). Dementia severity was assessed using the Dementia Severity Rating Scale. Frailty was assessed using the FRAIL-NH scale. Dependence in ADLs was assessed using the Katz ADL scale.
resultsThe median age of participants was 87 years (interquartile range 81-92). Over one-third of participants (n=86, 36%) had 5 or more daily medication administration times. The number of daily administration times and MRCI scores were positively correlated with resident length of stay (r
conclusionResidents with longer lengths of stay, more dependent in ADLs and most frail had the most complex medication regimens and, therefore, may benefit from targeted strategies to reduce medication regimen complexity.
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