ReviewHippokratia
Postoperative cognitive disorders: an update.
Review in Hippokratia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The economic burden of anesthetic-related adverse events: a systematic review and empirical analysis.BMC anesthesiology · 2025Pooled it
- Outcomes associated with postoperative cognitive dysfunction: a systematic review and meta-analysis.Age and ageing · 2024Pooled it
- Relationship between postoperative biomarkers of neuronal injury and postoperative cognitive dysfunction: A meta-analysis.PloS one · 2023Pooled it
- Trial
- Cognitive dysfunction after cardiac surgery: A systematic review and meta-analysis on the mini-mental state examination findings.Biomedical reports · 2026Article
- HEs Consciousness Scale: a rapid and promising classification for early assessment of post-anesthesia consciousness recovery.Journal of thoracic disease · 2025Article
- Amplitude of low-frequency fluctuation (ALFF) alterations in heart transplant patients with cognitive impairment: a resting-state fMRI study.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
- Sevoflurane versus propofol on immediate postoperative cognitive dysfunction in patients undergoing cardiac surgery under cardiopulmonary bypass: a comparative analysis.Journal of cardiothoracic surgery · 2025Article
- Knowledge, attitudes, and practices regarding Post-anesthesia cognitive dysfunction in patients undergoing gastrointestinal endoscopy.BMC anesthesiology · 2024Article
- The Association of Cerebral Oxygen Desaturation with Postoperative Cognitive Dysfunction in Older Patients: A Review.Clinical interventions in aging · 2024Review
- Effects of cognitive status on outcomes of groin hernia repair using various anesthesia techniques.Hernia : the journal of hernias and abdominal wall surgery · 2023Article
- The impact of circulatory arrest with selective antegrade cerebral perfusion on brain functional connectivity and postoperative cognitive function.Scientific reports · 2023Article
- CABG Patients Develop Global DNA Hypermethylation, That Negatively Affect the Mitochondrial Function and Promote Post-Surgical Cognitive Decline: A Proof of Concept in Small Cohort.Journal of clinical medicine · 2023Article
- Peri-Operative Risk Factors Associated with Post-Operative Cognitive Dysfunction (POCD): An Umbrella Review of Meta-Analyses of Observational Studies.Journal of clinical medicine · 2023Review
- Dexmedetomidine Restores Autophagic Flux, Modulates Associated microRNAs and the Cholinergic Anti-inflammatory Pathway upon LPS-Treatment in Rats.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2022Article
- Impairment of Cognitive Function in Different Domains Early After Lung Transplantation.Journal of clinical psychology in medical settings · 2022Observational
- An Update on Postoperative Cognitive Dysfunction Following Cardiac Surgery.Frontiers in psychiatry · 2022Review
- IS IT TIME TO REDEFINE COGNITIVE DYSFUNCTION AFTER CARDIAC SURGERY? THE IMPORTANCE OF METHODOLOGICAL CONSISTENCY.Acta clinica Croatica · 2021Review
- Neurofilament light: a narrative review on biomarker utility.Faculty reviews · 2021Review
- Suppression of behavioral activity and hippocampal noradrenaline caused by surgical stress in type 2 diabetes model mice.BMC neuroscience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCognitive dysfunction is a common complication after surgery. It is a major cause for increased, sometimes long-term, morbidity and mortality.
methodsIn this narrative review we performed a literature search regarding postoperative cognitive decline regarding risk factors, the type of surgical intervention, potential neuroprotective effects of anesthetic drugs, and associated quality of life and healthcare costs.
resultsSeveral risk factors are implicated in postoperative cognitive impairment. Cardiac surgery and specific orthopedic interventions are associated with a higher incidence of postoperative cognitive disorders. Results regarding the neuroprotective effects of anesthetics agents are still controversial but promising. Postoperative cognitive alterations are a major public healthcare issue as they impair the everyday quality of life, and expand the yearlong expenses.
conclusionsPostoperative cognitive disorders are devastating, potentially life-threatening complications. High-suspicion, especially in high-risk patients and operations, and adoption of available neuroprotective strategies may prove lifesaving. HIPPOKRATIA 2018, 22(4): 147-154.
Indexed as
Identifiers
31695301PMC6825421What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.