ArticleThe Saudi dental journal2019
Pulpal repair after direct pulp capping with new bioceramic materials: A comparative histological study.
Article in The Saudi dental journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The trial behind it
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Short-term dentin-pulp complex repair with four pulp capping materials: a double-blind randomized crossover histological study.Scientific reports · 2025Trial
- Histological Tissue Response to Calcium Silicate-Based Cements Assessed in Human Tooth Culture Models: A Systematic Review.Journal of functional biomaterials · 2026Review
- Incorporation of selenium nanoparticles into mineral trioxide aggregate used as a direct pulp capping material.Biomaterial investigations in dentistry · 2026Article
- In Vitro Assessment of the Effects of Endodontic Sealers on Cell Viability, Adhesion, and Migration.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2025Article
- Phytotherapy in Pediatric Dentistry: A Narrative Review of Clinical Applications and Evidence.Children (Basel, Switzerland) · 2025Review
- Bioactivity and biocompatibility of bioceramic-based pulp capping materials in laboratory and animal models.Journal of materials science. Materials in medicine · 2025Article
- Comparative evaluation of various direct pulp capping materials using different blood derivatives on disease-free tooth: A histopathological assessment case series.Journal of conservative dentistry and endodontics · 2025Article
- Effect of Vital Pulp Therapy Biomaterials on Tooth Discolouration: A Review of the Literature.International journal of biomaterials · 2025Review
- Tissue engineering approaches for dental pulp regeneration: The development of novel bioactive materials using pharmacological epigenetic inhibitors.Bioactive materials · 2024Review
- Different pulp capping agents and their effect on pulp inflammatory response: A narrative review.The Saudi dental journal · 2024Review
- The Management of Hyperplastic Pulpitis in Immature Permanent Molar Using Vital Pulp Therapy: A Case Report with 12 Months Follow-Up.Case reports in dentistry · 2024Article
- A paradigm shift from calcium hydroxide to bioceramics in direct pulp capping: A narrative review.Journal of conservative dentistry and endodontics · 2024Review
- Advances and challenges in regenerative dentistry: A systematic review of calcium phosphate and silicate-based materials on human dental pulp stem cells.Materials today. Bio · 2023Review
- Biomimetic Approaches in Clinical Endodontics.Biomimetics (Basel, Switzerland) · 2022Review
- Direct pulp capping with autologous bone marrow derived stem cells in dogs.Veterinary research forum : an international quarterly journal · 2022Article
- A prospective clinical study with one year follow up of deep caries management using a novel biomaterial.BMC research notes · 2022Article
- A critical analysis of research methods and experimental models to study biocompatibility of endodontic materials.International endodontic journal · 2022Review
- Efficacy of different calcium silicate materials as pulp-capping agents: Randomized clinical trial.Journal of dental sciences · 2021Article
- Premixed bioceramics: A novel pulp capping agent.Journal of conservative dentistry : JCDReview
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo histopathologically evaluate the pulpal healing after direct pulp capping with TotalFill and compared it with Neo MTA Plus in human tooth cultures.
methodsForty sound human premolars freshly extracted for orthodontic reasons were randomly assigned to two experimental groups; group I: TotalFill and group II: Neo MTA Plus. Standardized Class V cavities were prepared on the buccal surface of each tooth where the pulp exposure was performed with a dental explorer. The pulp-exposed teeth were immediately capped with one of the tested materials. The prepared cavities were then finally restored with glass-ionomer cement. Teeth were cultured for three weeks and three months. Then, the cultured teeth were demineralized, sectioned and stained for histopathological evaluation. Data collected and statistically analyzed by using Fisher's exact test. The significance level was set at P ≤ 0.05.
resultsHistopathological analysis showed complete dentin bridge formation and an absence of inflammatory pulp response. Statistical analysis showed no significant differences between the TotalFill and Neo MTA Plus groups during the observation periods. However, a significantly higher thickness of the dentin bridge was found in the group of teeth treated with TotalFill at three months.
conclusionsTotalFill produced similar favorable pulp healing and repair, and were comparable to Neo MTA Plus. Furthermore, TotalFill can form a thicker dentin bridge compared with Neo MTA Plus.
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Registered trials
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