Evidence map›Paper›PMID 31695137›Full record

ArticleScientific reports2019

Green solvents and Ultrasound-Assisted Extraction of bioactive orange (Citrus sinensis) peel compounds.

Abigail Montero-Calderon, Clara Cortes, Ana Zulueta, Ana Frigola, Maria J Esteve

Abstract readEvaluation Study
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  9. Hesperidin from Orange Peel as a Promising Skincare Bioactive: An Overview.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abigail Montero-CalderonDepartment of Nutrition and Food Chemistry, University of Valencia, Avda. Vicent Andrés Estellés, s/n, 46100, Burjassot, Spain.ORCID http://orcid.org/0000-0001-8219-8695
Clara CortesDepartment of Nutrition and Food Chemistry, University of Valencia, Avda. Vicent Andrés Estellés, s/n, 46100, Burjassot, Spain.
Ana ZuluetaDepartment of Nutrition and Food Chemistry, University of Valencia, Avda. Vicent Andrés Estellés, s/n, 46100, Burjassot, Spain.
Ana FrigolaDepartment of Nutrition and Food Chemistry, University of Valencia, Avda. Vicent Andrés Estellés, s/n, 46100, Burjassot, Spain.
Maria J EsteveDepartment of Nutrition and Food Chemistry, University of Valencia, Avda. Vicent Andrés Estellés, s/n, 46100, Burjassot, Spain. maria.jose.esteve@uv.es.ORCID http://orcid.org/0000-0002-4468-7233

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Byproducts such as orange peel have potential uses because of their bioactive compounds, which are important for their potential to reduce the risk factors of diseases caused by aging. The lack of effective techniques and the high levels of pollution produced by the conventional extraction of bioactive compounds using organic solvents have highlighted the need to enhance the 'green chemistry' trend. This study evaluates the use of ultrasound to extract bioactive compounds from orange peel. The antioxidant capacity, phenolic content, ascorbic acid, total carotenoids, and HPLC profile of phenolic compounds from orange peel extracts were obtained by a physicochemical evaluation. The results demonstrate that the optimal conditions for the ultrasound-assisted extraction of bioactive orange peel compounds were a power of 400 W, a time of 30 min, and 50% ethanol in water. These conditions were used to obtain a total carotenoid concentration of 0.63 mg ß-carotene/100 g, vitamin C concentration of 53.78 mg AA/100 g, phenolic concentration of 105.96 mg GAE/100 g, and antioxidant capacity of ORAC = 27.08 mM TE and TEAC = 3.97 mM TE. The major phenolic compound identified in all orange peel extracts was hesperidin, with a maximum concentration of 113.03 ± 0.08 mg/100 g.

Indexed as

AntioxidantsCarotenoidsChemical FractionationCitrus sinensisFruitGreen Chemistry TechnologyPhenolsPlant ExtractsUltrasonicsAntioxidantsCarotenoidsPhenolsPlant Extracts

Identifiers

PMID31695137
PMCPMC6834654

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.