Evidence map›Paper›PMID 31695055›Full record

ArticleScientific reports2019

Differential effects of D-cycloserine and amantadine on motor behavior and D

Susanne Nikolaus, Hans-Jörg Wittsack, Frithjof Wickrath, Anja Müller-Lutz, Hubertus Hautzel, Markus Beu, Christina Antke, Eduards Mamlins, Maria Angelica De Souza Silva, Joseph P Huston and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Susanne NikolausClinic of Nuclear Medicine, University Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, D-40225, Düsseldorf, Germany. susanne.nikolaus@uni-duesseldorf.de.
Hans-Jörg WittsackDepartment of Diagnostic and Interventional Radiology, University Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, D-40225, Düsseldorf, Germany.
Frithjof WickrathInstitute for Clinical Diabetology, German Diabetes Center (DDZ), Heinrich-Heine University, Auf´m Hennekamp 65, 40225, Düsseldorf, Germany.
Anja Müller-LutzDepartment of Diagnostic and Interventional Radiology, University Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, D-40225, Düsseldorf, Germany.
Hubertus HautzelClinic for Nuclear Medicine, University Hospital Essen, Hufelandstraße 55, D-45122, Essen, Germany.
Markus BeuClinic of Nuclear Medicine, University Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, D-40225, Düsseldorf, Germany.
Christina AntkeClinic of Nuclear Medicine, University Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, D-40225, Düsseldorf, Germany.
Eduards MamlinsClinic of Nuclear Medicine, University Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, D-40225, Düsseldorf, Germany.
Maria Angelica De Souza SilvaCenter for Behavioural Neuroscience, Institute of Experimental Psychology, Heinrich-Heine University, Universitätsstr. 1, D-40225, Düsseldorf, Germany.
Joseph P HustonCenter for Behavioural Neuroscience, Institute of Experimental Psychology, Heinrich-Heine University, Universitätsstr. 1, D-40225, Düsseldorf, Germany.
Gerald AntochDepartment of Diagnostic and Interventional Radiology, University Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, D-40225, Düsseldorf, Germany.
Hans-Wilhelm MüllerClinic of Nuclear Medicine, University Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, D-40225, Düsseldorf, Germany.
Düsseldorf University Hospital · DEHeinrich Heine University Düsseldorf · DEDeutsches Diabetes-Zentrum e.V. · DEEssen University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

D-cycloserine (DCS) and amantadine (AMA) act as partial NMDA receptor (R) agonist and antagonist, respectively. In the present study, we compared the effects of DCS and AMA on dopamine D

Indexed as

AmantadineAnimalsCycloserineDopamineExploratory BehaviorMaleMotor ActivityNucleus AccumbensProtein BindingRatsRats, WistarReceptors, Dopamine D2Receptors, Dopamine D3Substantia NigraThalamusVentral Tegmental AreaAmantadineCycloserineDopamineReceptors, Dopamine D2Receptors, Dopamine D3

Identifiers

PMID31695055
PMCPMC6834679
OpenAlexW2985511657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.