ReviewNature communications2019
Evolving perspectives on the sources of the frequency-following response.
Review in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05214092 (Cortical Contributions to Frequency-Following Response Generation and Modulation; Post-Operative Outcomes), which is not on this map. Cited by 102 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cortical Contributions to Frequency-Following Response Generation and Modulation; Post-Operative Outcomes
Who cites it
102 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Frequency-Following Responses in Sensorineural Hearing Loss: A Systematic Review.Journal of the Association for Research in Otolaryngology : JARO · 2024Pooled it
- Brainstem evoked auditory potentials in tinnitus: A best-evidence synthesis and meta-analysis.Frontiers in neurology · 2022Pooled it
- Electrophysiological Screening for Children With Suspected Auditory Processing Disorder: A Systematic Review.Frontiers in neurology · 2021Pooled it
- Comparing physiological signatures of synaptopathic noise exposure and carboplatin-induced inner-hair-cell dysfunction in chinchillas.Hearing research · 2026Article
- The Cortical Contribution to the Speech-Frequency-Following Response Is Not Modulated by Visual Information.The European journal of neuroscience · 2026Article
- Motor signals modulate cortical but not subcortical processing of self-initiated sounds.bioRxiv : the preprint server for biology · 2026Article
- Neurophysiological Evidence for Reduced Use of Prior Sound Patterns to Shape Speech Processing in Autism.bioRxiv : the preprint server for biology · 2026Article
- Linking Auditory Brainstem Neural Stability to Parent-Reported Autistic Traits in School-Age Children.Brain sciences · 2026Article
- Sound-evoked auditory neurophysiological signals are a window into prodromal functional differences in a preclinical model of Alzheimer's disease.Scientific reports · 2026Article
- Evaluating neural encoding of prosody-related F0 changes in emotional speech using the speech FFR in normal-hearing adults.Scientific reports · 2026Article
- Effect of Lateralization, Age, and Sex on Frequency Following Response in Children: Neural Speech Encoding to a 170 ms [da] Stimulus.Life (Basel, Switzerland) · 2026Article
- Time-efficient Methodology for Robustly Assessing Speech-related Mismatch Responses in Adults and Infants.Journal of cognitive neuroscience · 2026Article
- Demonstration of Alpha-Band Entrainment via Low-Field Magnetic Stimulation: A Simulation-Driven Proof of Concept.Bioengineering (Basel, Switzerland) · 2026Article
- Event-Related Brain Potentials and Frequency-Following Response to Syllables in Newborns and Adults.The European journal of neuroscience · 2026Article
- Neural speech encoding advantages associated with higher socioeconomic status extend to noise conditions with differential susceptibility.Frontiers in psychology · 2026Article
- Article
- Brainstem encoding of speech in the extended high frequencies and its behavioral correlates.Journal of neurophysiology · 2026Article
- Bilingual Exposure and Sex Shape Developmental Trajectories of Brain Responses to Speech-Sound Features in Infants.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Optimized Simultaneous Assessment of Subcortical and Cortical Auditory Responses Through a Frequency-Tagged Roving Paradigm.The European journal of neuroscience · 2025Review
- Neural Coding of Fundamental Frequency and Processing of Discrete Pitch Accents in Middle Age.The European journal of neuroscience · 2025Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The auditory frequency-following response (FFR) is a non-invasive index of the fidelity of sound encoding in the brain, and is used to study the integrity, plasticity, and behavioral relevance of the neural encoding of sound. In this Perspective, we review recent evidence suggesting that, in humans, the FFR arises from multiple cortical and subcortical sources, not just subcortically as previously believed, and we illustrate how the FFR to complex sounds can enhance the wider field of auditory neuroscience. Far from being of use only to study basic auditory processes, the FFR is an uncommonly multifaceted response yielding a wealth of information, with much yet to be tapped.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.