Evidence map›Paper›PMID 31694963›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Differential Coding Strategies in Glutamatergic and GABAergic Neurons in the Medial Cerebellar Nucleus.

Orçun Orkan Özcan, Xiaolu Wang, Francesca Binda, Kevin Dorgans, Chris I De Zeeuw, Zhenyu Gao, Ad Aertsen, Arvind Kumar, Philippe Isope

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 34 citations in OpenAlex.

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  5. Coordination of spike timing among the neurons of the cerebellum.bioRxiv : the preprint server for biology · 2025
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  6. Review
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  9. Characterization of direct Purkinje cell outputs to the brainstem.bioRxiv : the preprint server for biology · 2024
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  18. Synchronous spiking of cerebellar Purkinje cells during control of movements.Proceedings of the National Academy of Sciences of the United States of America · 2022
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  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Orçun Orkan ÖzcanCentre National de la Recherche Scientifique, Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, F-67000 Strasbourg, France.
Xiaolu WangDepartment of Neuroscience, Erasmus MC, 1105 BA Rotterdam, The Netherlands.
Francesca BindaCentre National de la Recherche Scientifique, Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, F-67000 Strasbourg, France.
Kevin DorgansCentre National de la Recherche Scientifique, Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, F-67000 Strasbourg, France.
Chris I De ZeeuwDepartment of Neuroscience, Erasmus MC, 1105 BA Rotterdam, The Netherlands.
Zhenyu GaoDepartment of Neuroscience, Erasmus MC, 1105 BA Rotterdam, The Netherlands.
Ad AertsenFaculty of Biology, University of Freiburg, Freiburg 79104, Germany.ORCID 0000-0002-8596-6888
Arvind KumarBernstein Center Freiburg, University of Freiburg, Freiburg 79104, Germany, and.ORCID 0000-0002-8044-9195
Philippe IsopeCentre National de la Recherche Scientifique, Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, F-67000 Strasbourg, France, philippe.isope@inci-cnrs.unistra.fr.ORCID 0000-0002-0630-5935
Institut des Neurosciences Cellulaires et Intégratives · FRErasmus MC · NLUniversity of Freiburg · DENetherlands Institute for Neuroscience · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cerebellum drives motor coordination and sequencing of actions at the millisecond timescale through adaptive control of cerebellar nuclear output. Cerebellar nuclei integrate high-frequency information from both the cerebellar cortex and the two main excitatory inputs of the cerebellum: the mossy fibers and the climbing fiber collaterals. However, how nuclear cells process rate and timing of inputs carried by these inputs is still debated. Here, we investigate the influence of the cerebellar cortical output, the Purkinje cells, on identified cerebellar nuclei neurons

Indexed as

Action PotentialsAfferent PathwaysAnesthesiaAnimalsCerebellar NucleiChannelrhodopsinsGABAergic NeuronsGenes, ReporterGlutamate DecarboxylaseGlutamic AcidInterneuronsMaleMiceMice, Inbred C57BLMotor SkillsNeuronsChannelrhodopsinsGlutamate Decarboxylaseglutamate decarboxylase 2Glutamic AcidSlc17a6 protein, mouseVesicular Glutamate Transport Protein 2cerebellar nucleicerebellumelectrophysiology in vivoPurkinje cellstemporal coding

Identifiers

PMID31694963
PMCPMC6939494
OpenAlexW2988913475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.