ArticleThe Journal of biological chemistry2019
Photic generation of 11-
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In one paragraph
Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- The expression of opsins in the human skin and its implications for photobiomodulation: A Systematic Review.Photodermatology, photoimmunology & photomedicine · 2020Pooled it
- Exploring Polyene Construction Tactics for the Total Synthesis of Ocular Pyridinium Bisretinoids of Lipofuscin A2E and pdA2E.The Journal of organic chemistry · 2026Article
- RGR-Mediated Photopic Visual Cycle and Oxidative Stress: Potential Mechanisms for Cone Vision Impairment and Retinal Degeneration in Retinitis Pigmentosa Linked to D1080N-IRBP.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Enantiopure Pyridinium Bisretinoids of Ocular Lipofuscin with Hexahydrobenzofuran Structure: Total Synthesis and Structure-Dependent Aggregated Morphology.The Journal of organic chemistry · 2026Article
- Retinol tracing within murine neural retina reveals cell type-specific retinol transport and distribution.The Journal of clinical investigation · 2026Article
- DIO3 coordinates photoreceptor development timing and fate stability in human retinal organoids.Genes & development · 2026Article
- The photoreceptive and neuroendocrine pineal organ of Atlantic salmon.Frontiers in physiology · 2026Article
- Stereochemical Reassignment by Total Synthesis of an Ocular Pyridinium Bisretinoid of Retinal Pigment Epithelium Lipofuscin:Organic letters · 2025Article
- Mechanisms and Functions of Chromophore Regeneration in the Classical Visual Cycle: Implications for Retinal Disease Pathogenesis and Therapy.Biomolecules · 2025Review
- Discovery and design of photocyclic animal opsins: potential application to gene therapy from non-visual opsin research.Eye and vision (London, England) · 2025Review
- The physiology of dark adaptation: Progress and future directions.Progress in retinal and eye research · 2025Review
- Retinoid dynamics in vision: from visual cycle biology to retina disease treatments.Pharmacology & therapeutics · 2025Review
- Germline Disruption of Retinal Pigment Epithelium-Expressed Zebrafish rlbp1bFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Advances and therapeutic opportunities in visual cycle modulation.Progress in retinal and eye research · 2025Review
- Expression of proteins supporting visual function in heterobranch gastropods.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2025Article
- The cone visual cycle and its disorders: insights from zebrafish.Frontiers in molecular neuroscience · 2025Review
- Vitamin A supply in the eye and establishment of the visual cycle.Current topics in developmental biology · 2025Review
- Ablation of Fatty Acid Transport Protein-4 Enhances Cone Survival, M-cone Vision, and Synthesis of Cone-Tropic 9-The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Dominant role for pigment epithelial CRALBP in supplying visual chromophore to photoreceptors.Cell reports · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Jianye ZhangGavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, California 92697.
Elliot H ChoiGavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, California 92697.
Aleksander TworakGavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, California 92697.
David SalomGavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, California 92697.ORCID 0000-0002-3208-1509
Henri LeinonenGavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, California 92697.ORCID 0000-0002-0388-832X
Christopher L SanderGavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, California 92697.ORCID 0000-0002-1680-6637
Thanh V HoangSolomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
James T HandaDepartment of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287.
Seth BlackshawSolomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.ORCID 0000-0002-1338-8476
Grazyna PalczewskaDepartment of Medical Devices, Polgenix, Inc., Irvine, California 92617.ORCID 0000-0003-4030-4685
Philip D KiserDepartment of Physiology and Biophysics, University of California, Irvine, California 92697.ORCID 0000-0003-1184-9539
Krzysztof PalczewskiGavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, California 92697 kpalczew@uci.edu.ORCID 0000-0002-0788-545X
University of California, Irvine · USJohns Hopkins University · USCleveland Medical Devices · US
Funding
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007250 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI HUANG, ALEX YEE-CHEN · 1985 to 2023
$33.4MSTRUCTURAL STUDIES OF ARRESTINSR01EY009339 · NEI · UNIVERSITY OF WASHINGTON · PI KISER, PHILIP DAVID, PALCZEWSKI, KRZYSZTOF · 1992 to 2025
$16.0MUse of systems pharmacology to prevent rod and cone photoreceptor degenerationR24EY027283 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI PALCZEWSKI, KRZYSZTOF · 2017 to 2021
$7.9MVISUAL SCIENCES TRAINING PROGRAMT32EY007157 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI Johannes Friedrich von Lintig · 2000 to 2026
$5.5MTranscriptional regulation of retinal cell differentiation and functionR01EY020560 · NEI · JOHNS HOPKINS UNIVERSITY · PI BLACKSHAW, SETH · 2011 to 2021
$4.4MPREDOCTORAL TRAINING PROGRAM IN MOLECULAR THERAPEUTICST32GM008803 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI MIEYAL, JOHN J, NIEMAN, MARVIN THOMAS · 2001 to 2023
$4.2MMECHANISMS OF ADAPTATION IN MAMMALIAN CONESR01EY019312 · NEI · WASHINGTON UNIVERSITY · PI KEFALOV, VLADIMIR JIVKOV · 2009 to 2017
$3.3MA two-photon ophthalmoscope for human retinal imaging and functional testingU01EY025451 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI PALCZEWSKI, KRZYSZTOF · 2015 to 2019
$3.2MOxidative stress and innate immunity impair the visual cycleR01EY027691 · NEI · JOHNS HOPKINS UNIVERSITY · PI HANDA, JAMES T · 2017 to 2021
$2.7MBLRD VA IK2 BX002683NEI NIH HHS R01 EY009339NEI NIH HHS R01 EY019312NEI NIH HHS R01 EY020560NEI NIH HHS R01 EY027691NEI NIH HHS R24 EY027283NEI NIH HHS T32 EY007157NEI NIH HHS U01 EY025451NIGMS NIH HHS T32 GM007250NIGMS NIH HHS T32 GM008803
Abstract
Photoisomerization of the 11-
Indexed as
AnimalsCattleEye ProteinsHumansMiceModels, MolecularMolecular StructureReceptors, G-Protein-CoupledRetinaldehydeRetinal Pigment EpitheliumRNA-SeqStereoisomerismEye ProteinsG protein-coupled receptor RGRReceptors, G-Protein-CoupledRetinaldehydeG-protein–coupled receptor (GPCR)retinaretinoid-binding proteinretinolrhodopsin
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.