ReviewEmergency medicine journal : EMJ2020
Thromboprophylaxis in lower limb immobilisation after injury (TiLLI).
Review in Emergency medicine journal : EMJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence of venous thromboembolism in fracture below the knee with and without chemical thromboprophylaxis: a systematic review and meta-analysis.Archives of orthopaedic and trauma surgery · 2024Pooled it
- Vibration-stimulation device-assisted enhanced recovery after lower limb fracture surgery: A randomized controlled trial.International orthopaedics · 2026Trial
- Thromboprophylaxis in Non-operative Lower-Limb Immobilization: Risk Stratification Identifies Whom to Spare, Not Whom to Treat - A Narrative Review.Journal of orthopaedic case reports · 2026Article
- Article
- Admission to rehab increases risk of postoperative venous thromboembolism and bleeding after operative fixation of femoral neck fractures.Journal of orthopaedics · 2025Article
- Cost-Effectiveness Thresholds for Venous Thromboembolism Prophylaxis in Ankle Fracture Surgery: A Break-Even Analysis.Foot & ankle orthopaedics · 2025Article
- Minor trauma and venous thromboembolism: the threshold for antithrombotic prophylaxis.Haematologica · 2024Review
- Inconsistency in UK Biobank Event Definitions From Different Data Sources and Its Impact on Bias and Generalizability: A Case Study of Venous Thromboembolism.American journal of epidemiology · 2024Article
- Thromboembolic Events During Weightbearing vs Nonweightbearing Accelerated Rehabilitation Protocols for Complete Achilles Tendon Ruptures.Foot & ankle orthopaedics · 2023Article
- Trauma-Related Clinical Practice Variation in Dutch Emergency Departments.Healthcare (Basel, Switzerland) · 2023Article
- Characteristics of Deep Venous Thrombosis in Isolated Lower Extremity Fractures and Unsolved Problems in Guidelines: A Review of Recent Literature.Orthopaedic surgery · 2022Review
- Qualitative analysis of randomized controlled trials informing recommendations for venous thromboembolism prophylaxis after distal lower extremity injuries.OTA international : the open access journal of orthopaedic trauma · 2022Article
- Intervention to Improve Compliance With National Guidelines on Venous Thromboembolism Chemoprophylaxis for Patients With Operatively Managed Ankle Fractures.Ochsner journal · 2022Article
- Optimal management of older people with frailty non-weight bearing after lower limb fracture: a scoping review.Age and ageing · 2021Article
- In reply: Is it time to initiate venothromobolism prophylaxis for acute and ambulatory outpatients with lower limb immobilisation?Emergency medicine journal : EMJ · 2020Article
- What's new in VTE risk and prevention in orthopedic surgery.Research and practice in thrombosis and haemostasis · 2020Article
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9 authors.
Funding
Abstract
Venous thromboembolic disease is a major global cause of morbidity and mortality. An estimated 10 million episodes are diagnosed yearly; over half of these episodes are provoked by hospital admission/procedures and result in significant loss of disability adjusted life years. Temporary lower limb immobilisation after injury is a significant contributor to the overall burden of venous thromboembolism (VTE). Existing evidence suggests that pharmacological prophylaxis could reduce overall VTE event rates in these patients, but the proportional reduction of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.