Evidence map›Paper›PMID 31694853›Full record

ArticleG3 (Bethesda, Md.)2020

MicroRNAs Regulate Multiple Aspects of Locomotor Behavior in

Nathan C Donelson, Richa Dixit, Israel Pichardo-Casas, Eva Y Chiu, Robert T Ohman, Justin B Slawson, Mason Klein, Tudor A Fulga, David Van Vactor, Leslie C Griffith

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. MicroRNA-Dependent Control of Sensory Neuron Function Regulates Posture Behavior inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nathan C DonelsonDepartment of Biology and Volen National Center for Complex Systems, Brandeis University, Waltham, MA 02454.
Richa DixitDepartment of Cell Biology and Program in Neuroscience, Harvard Medical School, Boston, MA 02115, and.
Israel Pichardo-CasasDepartment of Cell Biology and Program in Neuroscience, Harvard Medical School, Boston, MA 02115, and.
Eva Y ChiuDepartment of Biology and Volen National Center for Complex Systems, Brandeis University, Waltham, MA 02454.
Robert T OhmanDepartment of Cell Biology and Program in Neuroscience, Harvard Medical School, Boston, MA 02115, and.
Justin B SlawsonDepartment of Biology and Volen National Center for Complex Systems, Brandeis University, Waltham, MA 02454.
Mason KleinDepartment of Physics, Harvard University, Cambridge, MA 02138.ORCID 0000-0001-8211-077X
Tudor A FulgaDepartment of Cell Biology and Program in Neuroscience, Harvard Medical School, Boston, MA 02115, and.
David Van VactorDepartment of Cell Biology and Program in Neuroscience, Harvard Medical School, Boston, MA 02115, and.ORCID 0000-0001-8156-9482
Leslie C GriffithDepartment of Biology and Volen National Center for Complex Systems, Brandeis University, Waltham, MA 02454, griffith@brandeis.edu davie@hms.harvard.edu.ORCID 0000-0003-3164-9876
Harvard University · USBrandeis University · US

Funding

Quantitative Neuroscience: Tools for Bridging Levels of AnalysisT32NS007292 · NINDS · BRANDEIS UNIVERSITY · PI GINA G TURRIGIANO · 1986 to 2026
$12.7M
NEUROSCIENCE: FROM CHANNELS TO BEHAVIORT32MH019929 · NIMH · BRANDEIS UNIVERSITY · PI GRIFFITH, LESLIE C · 1994 to 2023
$8.5M
GENETIC AND BIOCHEMICAL MECHANISMS OF REGULATIONT32GM007122 · NIGMS · BRANDEIS UNIVERSITY · PI LOVETT, SUSAN THOMAS · 1985 to 2020
$7.5M
Regulation of sleep by microRNAsP01NS090994 · NINDS · HARVARD MEDICAL SCHOOL · PI DAVIS, RONALD L · 2016 to 2020
$5.7M
Regulation of Synapse Morphogenesis in DrosophilaR01NS069695 · NINDS · HARVARD MEDICAL SCHOOL · PI VAN VACTOR, DAVID L. · 2010 to 2018
$3.3M
The Behavioral Role and Synpatic Localization of dCASK in Drosophila melanogasterF31NS064679 · NINDS · BRANDEIS UNIVERSITY · PI SLAWSON, JUSTIN · 2009 to 2011
$58k
NIGMS NIH HHS T32 GM007122NIMH NIH HHS T32 MH019929NINDS NIH HHS F31 NS064679NINDS NIH HHS P01 NS090994NINDS NIH HHS R01 NS069695NINDS NIH HHS T32 NS007292
6 · The paper itself

Abstract

Locomotion is an ancient and fundamental output of the nervous system required for animals to perform many other complex behaviors. Although the formation of motor circuits is known to be under developmental control of transcriptional mechanisms that define the fates and connectivity of the many neurons, glia and muscle constituents of these circuits, relatively little is known about the role of post-transcriptional regulation of locomotor behavior. MicroRNAs have emerged as a potentially rich source of modulators for neural development and function. In order to define the microRNAs required for normal locomotion in

Indexed as

AnimalsDrosophila melanogasterGanglia, InvertebrateLocomotionMicroRNAsMicroRNAsDrosophila melanogastermicroRNAmotor behavior

Identifiers

PMID31694853
PMCPMC6945011
OpenAlexW2983729657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.