Evidence map›Paper›PMID 31694658›Full record

ArticleLipids in health and disease2019

Omega-3 polyunsaturated fatty acids status and cognitive function in young women.

Rebecca L Cook, Helen M Parker, Cheyne E Donges, Nicholas J O'Dwyer, Hoi Lun Cheng, Katharine S Steinbeck, Eka P Cox, Janet L Franklin, Manohar L Garg, Helen T O'Connor

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lipids in health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Rebecca L CookFaculty of Health Sciences, Discipline of Exercise and Sport Science, The University of Sydney, PO Box 170, Lidcombe, NSW, 1825, Australia.
Helen M ParkerFaculty of Health Sciences, Discipline of Exercise and Sport Science, The University of Sydney, PO Box 170, Lidcombe, NSW, 1825, Australia.
Cheyne E DongesSchool of Exercise Science, Sport and Health, Charles Sturt University, Bathurst, NSW, Australia.
Nicholas J O'DwyerFaculty of Health Sciences, Discipline of Exercise and Sport Science, The University of Sydney, PO Box 170, Lidcombe, NSW, 1825, Australia.
Hoi Lun ChengAcademic Department of Adolescent Medicine, The Children's Hospital at Westmead, Westmead, NSW, Australia.
Katharine S SteinbeckAcademic Department of Adolescent Medicine, The Children's Hospital at Westmead, Westmead, NSW, Australia.
Eka P CoxFaculty of Health Sciences, Discipline of Exercise and Sport Science, The University of Sydney, PO Box 170, Lidcombe, NSW, 1825, Australia.
Janet L FranklinMetabolism and Obesity Services, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Manohar L GargSchool of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, Australia.
Helen T O'ConnorFaculty of Health Sciences, Discipline of Exercise and Sport Science, The University of Sydney, PO Box 170, Lidcombe, NSW, 1825, Australia. helen.oconnor@sydney.edu.au.
University of Sydney · AUCharles Sturt University · AURoyal Prince Alfred Hospital · AUUniversity of Newcastle Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResearch indicates that low omega-3 polyunsaturated fatty acid (n-3 PUFA) may be associated with decreased cognitive function. This study examined the association between n-3 PUFA status and cognitive function in young Australian women.

methodsThis was a secondary outcome analysis of a cross-sectional study that recruited 300 healthy women (18-35 y) of normal weight (NW: BMI 18.5-24.9 kg/m

resultsTwo hundred ninety-nine women (26.9 ± 5.4 y) completed the study (O3I data, n = 288). The ANOVA showed no overall group differences but a significant group × cognition domain interaction (p < 0.01). Post hoc tests showed that participants in the low O3I tertile group scored significantly lower on attention than the middle group (p = 0.01; ES = 0.45 [0.15-0.74]), while the difference with the high group was borderline significant (p = 0.052; ES = 0.38 [0.09-0.68]). After confounder adjustments, the low group had lower attention scores than both the middle (p = 0.01) and high (p = 0.048) groups. These findings were supported by univariate analyses which found significant group differences for the attention domain only (p = 0.004).

conclusionsCognitive function in the attention domain was lower in women with lower O3I, but still within normal range. This reduced but normal level of cognition potentially provides a lower baseline from which cognition would decline with age. Further investigation of individuals with low n-3 PUFA status is warranted.

Indexed as

CognitionAdolescentAdultAttentionBody Mass IndexCross-Sectional StudiesFatty Acids, Omega-3FemaleHumansMental Status and Dementia TestsObesityYoung AdultFatty Acids, Omega-3AttentionCognitionN-3 PUFAOmega-3Women

Identifiers

PMID31694658
PMCPMC6836340
OpenAlexW2988207059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.