ArticleBMC nephrology2019
Non-adherence to Haemodialysis, Interdialytic weight gain and cardiovascular mortality: a cohort study.
Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Executive summary of the Korean Society of Nephrology 2021 clinical practice guideline for optimal hemodialysis treatment.The Korean journal of internal medicine · 2022Guideline
- Korean Society of Nephrology 2021 Clinical Practice Guideline for Optimal Hemodialysis Treatment.Kidney research and clinical practice · 2021Guideline
- Nutritional counseling tailored to the patient's learning type and its impact on interdialytic weight gain in chronic hemodialysis patients.Jornal brasileiro de nefrologiaTrial
- Traditional Brazilian dietary pattern as a factor associated with lower prevalence of dynapenic abdominal obesity in hemodialysis patients.BMC nephrology · 2026Article
- Reducing Excessive Interdialytic Weight Gain in Young Hemodialysis Patients: A Quality Improvement Initiative.Kidney medicine · 2025Article
- Post-dialysis serum osmolality as a predictor of interdialytic weight gain in diabetic and non-diabetic hemodialysis patients: a cross-sectional study.Irish journal of medical science · 2025Article
- Social Support and Adherence to Treatment Regimens among Patients Undergoing Hemodialysis.Healthcare (Basel, Switzerland) · 2024Article
- Factors influencing self-care management in adult hemodialysis patients: An integrative review.Qatar medical journal · 2024Article
- Increased thoracic fluid content is associated with higher risk for pneumonia in patients undergoing maintenance hemodialysis.Renal failure · 2023Article
- Interdialytic weight gain is not associated with symptoms of depression or apathy in patients on chronic hemodialysis.International urology and nephrology · 2023Article
- Executive Summary of the Korean Society of Nephrology 2021 Clinical Practice Guideline for Optimal Hemodialysis Treatment.Kidney research and clinical practice · 2021Article
- Exploring the experiences and perceptions of haemodialysis patients observing Ramadan fasting: a qualitative study.BMC nephrology · 2021Article
- Non-adherence to hemodialysis, perception of the illness, and severity of advanced nephropathy.Jornal brasileiro de nefrologiaArticle
- Factors associated with nursing diagnoses in chronic kidney patients: a cross-sectional study.Revista CuidarteArticle
- The Effects of Peer Education on Treatment Adherence among Patients Receiving Hemodialysis: A Randomized Controlled Trial.Iranian journal of nursing and midwifery researchArticle
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6 authors at 1 institution in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with chronic kidney diseases (CKD) on haemodialysis (HD) have high morbidity and mortality rates, which are also due to the inherent risks associated with nephropathy. Non-adherence (NA) to the different demands of the treatment can have consequences for the outcome of patients undergoing HD; nevertheless, there are still doubts about such repercussions. This study was conducted to evaluate the association between NA to conventional HD and all-cause mortality and cardiovascular mortality.
methodsWe prospectively evaluated mortality in a 6-year period in a cohort of 255 patients on HD in northeast Brazil. The evaluated parameters of NA to HD were interdialytic weight gain (IDWG) ≥ 4% of dry weight (DW), hyperphosphatemia and regular attendance at treatment, assessed as the correlation between the periods on HD completed and those prescribed. We used the Cox multivariate regression model to analyse survival and the predictors of all-cause mortality and cardiovascular mortality.
resultsWith a median follow-up period of 1493 days and a mortality rate of 9.1 per 100 people-years, there were 87 deaths, of which 54% were cardiovascular deaths. IDWG ≥4% of DW was associated with a risk of all-cause mortality however presenting a borderline outcome for cardiovascular mortality, with hazard ratios of 2.02 (CI 95% 1.17-3.49, p = 0.012) and 2.09 (CI 95% 1.01-4.35, p = 0.047), respectively. No significant association was found between other parameters of NA and mortality. Subgroup analysis showed that for patients with IDWG ≥4% of DW, malnutrition, age and diagnosis of cardiovascular and cerebrovascular diseases were associated with higher all-cause mortality.
conclusionsIDWG ≥4% of DW was identified as an independent predictor of all-cause mortality and demonstrated a borderline outcome for cardiovascular mortality in patients on conventional HD. The occurrence of excessive IDWG in the presence of malnutrition represented a significant increase in the risk of death, indicating a subgroup of patients with a worse prognosis.
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