ArticleBMC infectious diseases2019
The clinical features and prognosis of infective endocarditis in the elderly from 2007 to 2016 in a tertiary hospital in China.
Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 18 citations in OpenAlex.
- Article
- Specialty-Related Differences in Adherence to Antibiotic Therapy Guidelines for Infective Endocarditis in Older Patients.Antibiotics (Basel, Switzerland) · 2026Article
- Neutrophil percentage-to-albumin ratio as a predictor of In-hospital mortality in infective endocarditis.Biomarkers in medicine · 2025Article
- Anemia and Transfusion in Infective Endocarditis.Reviews in cardiovascular medicine · 2025Review
- Temporal trends, clinical characteristics and prognostic factors analysis of infective endocarditis: a multicenter ambispective cohort study in China.BMC cardiovascular disorders · 2025Article
- Postoperative follow-up of 221 patients with infective endocarditis from Gaoligong mountain area of Yunnan in China: a retrospective, single-center, observational cohort study.Journal of thoracic disease · 2024Article
- Clinical Presentation and Risk Factors of Infective Endocarditis in the Elderly: A Systematic Review.Journal of personalized medicine · 2023Review
- Blood Culture Negative Endocarditis: A Review of Laboratory Diagnostic Approaches.International journal of general medicine · 2023Review
- Comorbidity and Prognosis in Octogenarians with Infective Endocarditis.Journal of clinical medicine · 2022Article
- Native valve, prosthetic valve, and cardiac device-related infective endocarditis: A review and update on current innovative diagnostic and therapeutic strategies.Frontiers in cell and developmental biology · 2022Review
- Clinical Characteristics and Risk Factors for in-Hospital Mortality in 240 Cases of Infective Endocarditis in a Tertiary Hospital in China: A Retrospective Study.Infection and drug resistance · 2022Article
- Surgery Is Underused in Elderly Patients With Left-Sided Infective Endocarditis: A Nationwide Registry Study.Journal of the American Heart Association · 2021Article
- Infective Endocarditis in the Elderly: Distinct Characteristics.Arquivos brasileiros de cardiologia · 2021Article
- Surgical treatment for infective endocarditis in the ageing society: a nationwide retrospective study in Japan.Open heart · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundInfective endocarditis (IE) especially in the elderly is a serious disease, with a worse prognosis.
methodsA retrospective cohort study was conducted. A total of 405 patients with definite IE were divided into three groups: 205 patients under 50 years old, 141 patients between 50 and 64 years old and 59 patients over 65 years old.
resultsFor older patients, clinical symptoms such as fever, anemia, and heart murmur were as common as the younger patients. IE in old patients had more frequent nosocomial origin (P = 0.007) and tended to be more frequent with bad oral hygiene (p = 0.008). The most frequent isolated pathogens in the old groups was streptococci and coagulase-negative staphylococci. The old patients had a lower operation rate (40.7% vs 58.9% vs 62.4%, P = 0.012) and higher in-hospital mortality (20.3% vs 10.6% vs 8.8%, P = 0.044) compared with the younger patients. Surgical treatment was a significant predictor of one-year mortality even after adjusting for the confounders (HR = 2.45, 95% CI 1.027-10.598, P = 0.009). The one-year survival rate was higher for older patients with surgical intervention than those without (95.8% vs 68.6%, P = 0.007).
conclusionsOlder patients with IE presented with more comorbidities, bad oral hygiene, more nosocomial origin and a more severe prognosis than younger patients. Streptococci was the most frequent micro-organisms in this group. Surgery were underused in old patients and those with surgical treatment had better prognosis.
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