Evidence map›Paper›PMID 31694505›Full record

ArticleStroke2019

Stagnating National Declines in Stroke Mortality Mask Widespread County-Level Increases, 2010-2016.

Eric W Hall, Adam S Vaughan, Matthew D Ritchey, Linda Schieb, Michele Casper

Abstract read
In one paragraph

Article in Stroke, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. A dispensable role of mural cell-derived laminin-Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
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  20. Rural-urban differences in stroke risk.Preventive medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eric W HallFrom the Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (E.W.H.).
Adam S VaughanDivision for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, Atlanta, GA (A.S.V., M.D.R., L.S., M.C.).
Matthew D RitcheyDivision for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, Atlanta, GA (A.S.V., M.D.R., L.S., M.C.).
Linda SchiebDivision for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, Atlanta, GA (A.S.V., M.D.R., L.S., M.C.).
Michele CasperDivision for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, Atlanta, GA (A.S.V., M.D.R., L.S., M.C.).

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Background and Purpose- Recent national and state-level trends show a stalling or reversal of previously declining stroke death rates. These national trends may mask local geographic variation and changes in stroke mortality. We assessed county-level trends in stroke mortality among adults aged 35 to 64 and ≥65 years. Methods- We used data from National Vital Statistics Systems and a Bayesian multivariate space-time conditional autoregressive model to estimate age-standardized annual stroke death rates for 2010 through 2016 among middle-aged adults (35-64 years) and older adults (≥65 years) in US counties. We used log-linear regression models to estimate average annual and total percent change in stroke mortality during the period. Results- Nationally, the annual percent change in stroke mortality from 2010 to 2016 was -0.7% (95% CI, -4.2% to 3.0%) among middle-aged adults and -3.5% (95% CI, -10.7% to 4.3%) among older adults, resulting in 2016 rates of 15.0 per 100 000 and 259.8 per 100 000, respectively. Increasing county-level stroke mortality was more prevalent among middle-aged adults (56.6% of counties) compared with among older adults (26.1% of counties). About half (48.3%) of middle-aged adults, representing 60.2 million individuals, lived in counties in which stroke mortality increased. Conclusions- County-level increases in stroke mortality clarify previously reported national and state-level trends, particularly among middle-aged adults. Roughly 3×as many counties experienced increases in stroke death rates for middle-aged adults compared with older adults. This highlights a need to address stroke prevention and treatment for middle-aged adults while continuing efforts to reduce stroke mortality among the more highly burdened older adults. Efforts to reverse these troubling local trends will likely require joint public health and clinical efforts to develop innovative and integrated approaches for stroke prevention and care, with a focus on community-level characteristics that support stroke-free living for all.

Indexed as

AdultAgedFemaleHumansMaleMiddle AgedMortalityStrokeUnited Statesmiddle-agedmortality declinepublic healthstrokevital statistics

Identifiers

PMID31694505
PMCPMC6935863

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.