Evidence map›Paper›PMID 31694445›Full record

ArticleJournal of psychopharmacology (Oxford, England)2020

Effects of an adenosine A

Wesley Drew Gill, Heath W Shelton, Katherine C Burgess, Russell W Brown

Open access · bronzeAbstract read
In one paragraph

Article in Journal of psychopharmacology (Oxford, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Effects of positive mGlu5 modulation on DJournal of psychopharmacology (Oxford, England) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Adenosine ACells · 2020
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wesley Drew GillDepartment of Biomedical Sciences, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA.
Heath W SheltonDepartment of Biomedical Sciences, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA.
Katherine C BurgessDepartment of Biomedical Sciences, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA.
Russell W BrownDepartment of Biomedical Sciences, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA.ORCID 0000-0002-6512-7315
East Tennessee State University · US

Funding

The role of adenosine A(2A) receptor activation on the behavioral and plasticity response to nicotine in a rodent model of schizophreniaR15DA046926 · NIDA · EAST TENNESSEE STATE UNIVERSITY · PI BROWN, RUSSELL WAYNE · 2019 to 2019
$435k
NIDA NIH HHS R15 DA046926
6 · The paper itself

Abstract

backgroundAdenosine A

methodsRats were treated from postnatal day (P) 1 to P21 with saline or the dopamine D

resultsResults revealed that NQ treatment enhanced nicotine CPP, and both doses of CGS 21680 alleviated this enhancement. Nicotine also resulted in a CPP in controls, which was alleviated by both doses of CGS 21680. BDNF closely followed the behavioral results: CGS 21680 alleviated the enhancement in NAcc BDNF in NQ-treated animals, and eliminated the increase in NAcc BDNF produced by nicotine in controls. NQ-treated animals conditioned to nicotine resulted in an increase of NAcc GDNF, but this was eliminated by CGS 21680. Both BDNF and GDNF correlated with CPP performance.

conclusionsResults revealed that an adenosine A

Indexed as

RewardAdenosineAdenosine A2 Receptor AgonistsAnimalsBrain-Derived Neurotrophic FactorConditioning, PsychologicalGlial Cell Line-Derived Neurotrophic FactorMaleNeuronal PlasticityNicotineNucleus AccumbensPhenethylaminesQuinpiroleRatsSchizophrenia2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosineAdenosineAdenosine A2 Receptor AgonistsBrain-Derived Neurotrophic FactorGlial Cell Line-Derived Neurotrophic FactorNicotinePhenethylaminesQuinpiroleAdenosine A2A receptorsadolescenceBDNFdopamine D2 receptorGDNFnicotineschizophrenia

Identifiers

PMID31694445
PMCPMC9199013
OpenAlexW2950167217

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.