ArticleJournal of enzyme inhibition and medicinal chemistry2020
Design, synthesis and evaluation of quinolinone derivatives containing dithiocarbamate moiety as multifunctional AChE inhibitors for the treatment of Alzheimer's disease.
Article in Journal of enzyme inhibition and medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 48 citations in OpenAlex.
- Design and Synthesis of Novel β-Naphthol Dithiocarbamate Hybrids: A Convergent Multifaceted Approach Towards AChE and Amyloid-β Inhibition for Alzheimer's Disease.Molecular neurobiology · 2026Article
- Quinoline/thiazole compounds as selective acetylcholinesterase inhibitors: synthesis and biological assessment.RSC medicinal chemistry · 2026Article
- Novel Multi-Target Agents Based on the Privileged Structure of 4-Hydroxy-2-quinolinone.Molecules (Basel, Switzerland) · 2023Article
- Dithiocarbamates: Properties, Methodological Approaches and Challenges to Their Control.Toxics · 2023Review
- Synthesis and Evaluation of NovelPharmaceuticals (Basel, Switzerland) · 2022Article
- Sulfonamide-Derived Dithiocarbamate Gold(I) Complexes Induce the Apoptosis of Colon Cancer Cells by the Activation of Caspase 3 and Redox Imbalance.Biomedicines · 2022Article
- A Review of the Recent Developments of Molecular Hybrids Targeting Tubulin Polymerization.International journal of molecular sciences · 2022Review
- Design, Synthesis and Biological Evaluation of New 3,4-Dihydro-2(1Drug design, development and therapy · 2022Article
- Article
- Study on the Mechanism of Acori Graminei Rhizoma in the Treatment of Alzheimer's Disease Based on Network Pharmacology and Molecular Docking.BioMed research international · 2021Article
- Aryldiazoquinoline based multifunctional small molecules for modulating AβRSC advances · 2020Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A series of novel quinolinone derivatives bearing dithiocarbamate moiety were designed and synthesised as multifunctional AChE inhibitors for the treatment of AD. Most of these compounds exhibited strong and clearly selective inhibition to
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.