ArticleNeurospine2020
Biomaterials in Spinal Implants: A Review.
Article in Neurospine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 167 citations in OpenAlex.
- [Application of three-dimensional printed porous titanium alloy cage and poly-ether-ether-ketone cage in posterior lumbar interbody fusion].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2022Trial
- Comparison of Titanium and Carbon Fiber-Reinforced Polyetheretherketone Spinal Implants in Postoperative Spine Stereotactic Body Radiation Therapy: A Comprehensive Review of Current Evidence and Future Perspectives.Advances in radiation oncology · 2026Review
- Three dimensional printed patient-specific PEEK versus titanium mesh cage for anterior column reconstruction after spondylectomy for spinal tumours: a prospective controlled cohort study.International orthopaedics · 2026Article
- Preparation methods, mechano-bactericidal performance and mechanisms of Ti-based nanostructure arrays: A review.Discover nano · 2026Review
- A comprehensive review of biomechanical factors influencing pedicle screw fixation strength and the critical role of artificial intelligence.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- A comprehensive review of biomechanical factors influencing pedicle screw fixation strength and the critical role of artificial intelligence.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Review
- Innovations in Implant Osseointegration: Biomaterials, Surface Engineering, and Translational Strategies.Journal of biomedical materials research. Part A · 2026Review
- The Effect of Heat Treatment and Soaking in PBS Solution on the Strength Properties of PEEK Intended for Use in Orthopedics.Materials (Basel, Switzerland) · 2026Article
- Advancing Scoliosis Treatment with Patient-Specific Functionally Graded NiTi-SMA Rods: Key Considerations and Development Objectives.Bioengineering (Basel, Switzerland) · 2026Review
- Potential Applications of Additive Manufacturing in Intervertebral Disc Replacement Using Gyroid Structures with Several Thermoplastic Polyurethane Filaments.Biomedicines · 2026Article
- Comparison of Different Bipolar Construct Configurations for the Correction of Adult Spine Deformity: A Finite Element Analysis.Annals of biomedical engineering · 2025Article
- Advancements in biomaterials and bioactive solutions for lumbar spine fusion cages: Current trends and future perspectives.Bioactive materials · 2025Review
- Computational analysis of L4-L5 interspinous process devices and interbody fusion spacers using ceramic and polymeric materials via finite element modeling and artificial intelligence.Scientific reports · 2025Article
- Carbon-fiber-reinforced polyetheretherketone instrumentation in metastatic spine tumor surgery: technical considerations and potential pitfalls to avoid.Asian spine journal · 2025Article
- Screening of Metal Hypersensitivity in Pediatric Spine Surgery vs. Pectus Excavatum: A Comparative Cohort Study.Cureus · 2025Article
- Biomechanical analysis of trivergent, a new posterior lumbar spinal fixation system.North American Spine Society journal · 2025Article
- The Use of Non-Degradable Polymer (Polyetheretherketone) in Personalized Orthopedics-Review Article.Polymers · 2025Review
- Biomechanical and clinical evaluation of 3D-printed personalized vertebral implants after total En-Bloc spondylectomy: two-year follow-up outcomes.3D printing in medicine · 2025Article
- Poly(propylene fumarate)/hydroxyapatite nanocomposite/black phosphorus nanosheet phosphate composites for enhanced bone repair.Journal of orthopaedic surgery and research · 2025Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim to find the perfect biomaterial for spinal implant has been the focus of spinal research since the 1800s. Spinal surgery and the devices used therein have undergone a constant evolution in order to meet the needs of surgeons who have continued to further understand the biomechanical principles of spinal stability and have improved as new technologies and materials are available for production use. The perfect biomaterial would be one that is biologically inert/compatible, has a Young's modulus similar to that of the bone where it is implanted, high tensile strength, stiffness, fatigue strength, and low artifacts on imaging. Today, the materials that have been most commonly used include stainless steel, titanium, cobalt chrome, nitinol (a nickel titanium alloy), tantalum, and polyetheretherketone in rods, screws, cages, and plates. Current advancements such as 3-dimensional printing, the ProDisc-L and ProDisc-C, the ApiFix, and the Mobi-C which all aim to improve range of motion, reduce pain, and improve patient satisfaction. Spine surgeons should remain vigilant regarding the current literature and technological advancements in spinal materials and procedures. The progression of spinal implant materials for cages, rods, screws, and plates with advantages and disadvantages for each material will be discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.