Evidence map›Paper›PMID 31694296›Full record

ArticleViruses2019

The Porcine Deltacoronavirus Replication Organelle Comprises Double-Membrane Vesicles and Zippered Endoplasmic Reticulum with Double-Membrane Spherules.

Nicole Doyle, Philippa C Hawes, Jennifer Simpson, Lorin H Adams, Helena J Maier

Abstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  15. Translational control of coronaviruses.Nucleic acids research · 2020
    Review
  16. Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicole DoyleThe Pirbright Institute, Ash Road, Woking, Surrey GU24 0NF, UK.
Philippa C HawesThe Pirbright Institute, Ash Road, Woking, Surrey GU24 0NF, UK.ORCID 0000-0003-4665-9663
Jennifer SimpsonThe Pirbright Institute, Ash Road, Woking, Surrey GU24 0NF, UK.
Lorin H AdamsThe Pirbright Institute, Ash Road, Woking, Surrey GU24 0NF, UK.
Helena J MaierThe Pirbright Institute, Ash Road, Woking, Surrey GU24 0NF, UK.ORCID 0000-0002-2901-5578

Funding

Biotechnology and Biological Sciences Research Council BB/N002350/1Biotechnology and Biological Sciences Research Council BBS/E/I/00007034Biotechnology and Biological Sciences Research Council BBS/E/I/00007037Biotechnology and Biological Sciences Research Council BBS/E/I/00007038Biotechnology and Biological Sciences Research Council BBS/E/I/00007039
6 · The paper itself

Abstract

Porcine deltacoronavirus (PDCoV) was first identified in Hong Kong in 2012 from samples taken from pigs in 2009. PDCoV was subsequently identified in the USA in 2014 in pigs with a history of severe diarrhea. The virus has now been detected in pigs in several countries around the world. Following the development of tissue culture adapted strains of PDCoV, it is now possible to address questions regarding virus-host cell interactions for this genera of coronavirus. Here, we presented a detailed study of PDCoV-induced replication organelles. All positive-strand RNA viruses induce the rearrangement of cellular membranes during virus replication to support viral RNA synthesis, forming the replication organelle. Replication organelles for the

Indexed as

CoronavirusVirus ReplicationAnimalsCell LineCoronavirus InfectionsEndoplasmic ReticulumHost-Pathogen InteractionsIntracellular MembranesKineticsOrganellesRNA, ViralSwineRNA, ViralcoronavirusDMVdouble-membrane spheruledouble-membrane vesicleporcine deltacoronavirusreplication organellespherulezippered ER

Identifiers

PMID31694296
PMCPMC6893519

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.