ReviewToxins2019
A Review of the Effect of Trace Metals on Freshwater Cyanobacterial Growth and Toxin Production.
Review in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 103 citations in OpenAlex.
- When water turns toxic: how climate change drives cyanotoxin biosynthesis-A mechanistic review.World journal of microbiology & biotechnology · 2026Review
- Future-proofing the mixing zone concept in water resources management: an industrial perspective.Environmental science and pollution research international · 2026Article
- Influence of trace metal additions on the longevity of algal blooms across a productivity gradient.Journal of phycology · 2025Article
- Health and Environmental Impacts of Cyanobacteria and Cyanotoxins from Freshwater to Seawater.Toxins · 2025Review
- Spatiotemporal Variation in Dissolved, Bioavailable, and Particulate Elements and the Abundance of Harmful Algae in Grand Lake.ACS ES&T water · 2024Article
- Nanoscale elemental and morphological imaging of nitrogen-fixing cyanobacteria.Metallomics : integrated biometal science · 2024Article
- Review
- Understanding the Risks of Diffusion of Cyanobacteria Toxins in Rivers, Lakes, and Potable Water.Toxins · 2023Review
- The effects of salinity and N:P on N-rich toxins by both an N-fixing and non-N-fixing cyanobacteria.Limnology and oceanography letters · 2023Article
- Review
- Occurrence of Harmful Algal Blooms in Freshwater Sources of Mindu and Nyumba ya Mungu Dams, Tanzania.Journal of toxicology · 2023Article
- Integrated evaluation of the requirements and excretions of Cu, Fe, Zn, and Mn for broilers via a uniform design method.Frontiers in veterinary science · 2023Article
- The Influence of Micronutrient Trace Metals onToxins · 2022Article
- Growth at the limits: comparing trace metal limitation of a freshwater cyanobacterium (Dolichospermum lemmermannii) and a freshwater diatom (Fragilaria crotonensis).Scientific reports · 2022Article
- Nitrogen form, concentration, and micronutrient availability affect microcystin production in cyanobacterial blooms.Harmful algae · 2021Article
- Co-Occurrence of Cyanobacteria and Cyanotoxins with Other Environmental Health Hazards: Impacts and Implications.Toxins · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cyanobacterial blooms are becoming more common in freshwater systems, causing ecological degradation and human health risks through exposure to cyanotoxins. The role of phosphorus and nitrogen in cyanobacterial bloom formation is well documented and these are regularly the focus of management plans. There is also strong evidence that trace metals are required for a wide range of cellular processes, however their importance as a limiting factor of cyanobacterial growth in ecological systems is unclear. Furthermore, some studies have suggested a direct link between cyanotoxin production and some trace metals. This review synthesises current knowledge on the following: (1) the biochemical role of trace metals (particularly iron, cobalt, copper, manganese, molybdenum and zinc), (2) the growth limitation of cyanobacteria by trace metals, (3) the trace metal regulation of the phytoplankton community structure and (4) the role of trace metals in cyanotoxin production. Iron dominated the literature and regularly influenced bloom formation, with 15 of 18 studies indicating limitation or colimitation of cyanobacterial growth. A range of other trace metals were found to have a demonstrated capacity to limit cyanobacterial growth, and these metals require further study. The effect of trace metals on cyanotoxin production is equivocal and highly variable. Better understanding the role of trace metals in cyanobacterial growth and bloom formation is an essential component of freshwater management and a direction for future research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.