Evidence map›Paper›PMID 31694285›Full record

ArticleJournal of clinical medicine2019

Latika Puri, Jonathan M Flanagan, Guolian Kang, Juan Ding, Wenjian Bi, Beth M McCarville, Ralf B Loeffler, Aaryani Tipirneni-Sajja, Martha Villavicencio, Kristine R Crews and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Latika PuriDepartment of Hematology, St Jude Children's Research Hospital, Memphis, TN 38105, USA.
Jonathan M FlanaganDivision of Hematology, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Guolian KangDepartment of Biostatistics, St Jude Children's Research Hospital, Memphis, TN 38105, USA.
Juan DingDepartment of Biostatistics, St Jude Children's Research Hospital, Memphis, TN 38105, USA.
Wenjian BiDepartment of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
Beth M McCarvilleDepartment of Diagnostic Imaging, St Jude Children's Research Hospital, Memphis, TN 38105, USA.
Ralf B LoefflerDepartment of Research Imaging, University of New South Wales, Randwick, NSW 2052, Australia.ORCID 0000-0002-0482-5486
Aaryani Tipirneni-SajjaDepartment of Biomedical Engineering, University of Memphis, Memphis, TN 38105, USA.
Martha VillavicencioDepartment of Hematology, St Jude Children's Research Hospital, Memphis, TN 38105, USA.
Kristine R CrewsDepartment of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0002-7558-558X
Claudia M HillenbrandDepartment of Research Imaging, University of New South Wales, Randwick, NSW 2052, Australia.
Jane S HankinsDepartment of Hematology, St Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0003-4439-7321
St. Jude Children's Research Hospital · USUNSW Sydney · AUBaylor College of Medicine · USUniversity of Memphis · USUniversity of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic blood transfusions in patients with sickle cell anemia (SCA) cause iron overload, which occurs with a degree of interpatient variability in serum ferritin and liver iron content (LIC). Reasons for this variability are unclear and may be influenced by genes that regulate iron metabolism. We evaluated the association of the copy number of the glutathione S-transferase M1 (

Indexed as

chelation therapyglutathione S-transferase M1 (GSTM1)iron overloadsickle cell anemia

Identifiers

PMID31694285
PMCPMC6912836
OpenAlexW2983211437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.