Evidence map›Paper›PMID 31694281›Full record

ArticleSensors (Basel, Switzerland)2019

Analyte Quantity Detection from Lateral Flow Assay Using a Smartphone.

Kamrul H Foysal, Sung Eun Seo, Min Ju Kim, Oh Seok Kwon, Jo Woon Chong

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 67 citations in OpenAlex.

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  13. Point-of-Care Monitoring of Respiratory Diseases Using Lateral Flow Assay and CMOS Camera Reader.IEEE journal of translational engineering in health and medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Kamrul H FoysalDepartment of Electrical & Computer Engineering, Texas Tech University, Lubbock, TX 79409, USA.
Sung Eun SeoInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.
Min Ju KimInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.
Oh Seok KwonInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.
Jo Woon ChongDepartment of Electrical & Computer Engineering, Texas Tech University, Lubbock, TX 79409, USA.
Korea Research Institute of Bioscience and Biotechnology · KRTexas Tech University · USKorea University of Science and Technology · KR

Funding

Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries MAFRA (318104-3),Korea Research Institute of Bioscience and Biotechnology (KRIBB) Initiative Research ProgramNational Research Foundation of Korea NRF-2018M3C1B9069834, NRF-2019M3C1B8077, NRF-2016M3C7A1905384544,
6 · The paper itself

Abstract

Lateral flow assay (LFA) technology has recently received interest in the biochemical field since it is simple, low-cost, and rapid, while conventional laboratory test procedures are complicated, expensive, and time-consuming. In this paper, we propose a robust smartphone-based analyte detection method that estimates the amount of analyte on an LFA strip using a smartphone camera. The proposed method can maintain high estimation accuracy under various illumination conditions without additional devices, unlike conventional methods. The robustness and simplicity of the proposed method are enabled by novel image processing and machine learning techniques. For the performance analysis, we applied the proposed method to LFA strips where the target analyte is albumin protein of human serum. We use two sets of training LFA strips and one set of testing LFA strips. Here, each set consists of five strips having different quantities of albumin-10 femtograms, 100 femtograms, 1 picogram, 10 picograms, and 100 picograms. A linear regression analysis approximates the analyte quantity, and then machine learning classifier, support vector machine (SVM), which is trained by the regression results, classifies the analyte quantity on the LFA strip in an optimal way. Experimental results show that the proposed smartphone application can detect the quantity of albumin protein on a test LFA set with 98% accuracy, on average, in real time.

Indexed as

analyte detectionLFA padLFA readersmartphone

Identifiers

PMID31694281
PMCPMC6864604
OpenAlexW2985797996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.