Evidence map›Paper›PMID 31694243›Full record

ArticleMolecules (Basel, Switzerland)2019

Oleanolic Acid Acetate Exerts Anti-Inflammatory Activity via IKKα/β Suppression in TLR3-Mediated NF-κB Activation.

Hyung Jin Lim, Hyun-Jae Jang, Mi Hwa Kim, Soyoung Lee, Seung Woong Lee, Seung-Jae Lee, Mun-Chual Rho

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Chemical Characteristics and Antimicrobial Activity ofMolecules (Basel, Switzerland) · 2026
    Article
  4. Review
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  8. Review
  9. Regulatory Effects ofBioMed research international · 2022
    Article
  10. Immunomodulatory properties of triterpenes.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2022
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hyung Jin LimImmunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si 56212, Korea.
Hyun-Jae JangNatural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, 30 Yeongudanji-ro, Cheongju-si 28116, Korea.ORCID 0000-0002-4383-4465
Mi Hwa KimImmunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si 56212, Korea.
Soyoung LeeImmunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si 56212, Korea.
Seung Woong LeeImmunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si 56212, Korea.ORCID 0000-0003-1025-7363
Seung-Jae LeeImmunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si 56212, Korea.
Mun-Chual RhoImmunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si 56212, Korea.
Korea Research Institute of Bioscience and Biotechnology · KR

Funding

Korea Institute for Advancement of Technology P0000811Korea Research Institute of Bioscience and Biotechnology KGS1081911Korea Research Institute of Bioscience and Biotechnology KGS9531911Ministry of Science, ICT and Future Planning 2015K000281
6 · The paper itself

Abstract

Oleanolic acid acetate (OAA), a major triterpenoid compound of

Indexed as

AcetatesAnti-Inflammatory AgentsCell LineCytokinesDown-RegulationGene ExpressionHumansI-kappa B KinaseInflammationMacrophagesMitogen-Activated Protein KinasesNF-kappa BOleanolic AcidSignal TransductionToll-Like Receptor 3AcetatesAnti-Inflammatory AgentsCytokinesI-kappa B KinaseMitogen-Activated Protein KinasesNF-kappa BOleanolic AcidTLR3 protein, humanToll-Like Receptor 3inflammatory cytokinesIκB kinase α/βoleanolic acid acetatetoll-like receptorsVigna angularis

Identifiers

PMID31694243
PMCPMC6866124
OpenAlexW2984624425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.