Evidence map›Paper›PMID 31694231›Full record

ArticleNutrients2019

Arterial Stiffness, Sugar-Sweetened Beverages and Fruits Intake in a Rural Population Sample: Data from the Brisighella Heart Study.

Arrigo F G Cicero, Federica Fogacci, Giovambattista Desideri, Elisa Grandi, Elisabetta Rizzoli, Sergio D'Addato, Claudio Borghi

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Arrigo F G CiceroHypertension and Atherosclerosis Research Group, Medical and Surgical Sciences Department; Sant'Orsola-Malpighi University Hospital, Building 2-IV Floor, Via Albertoni 15, 40138 Bologna, Italy.ORCID 0000-0002-4367-3884
Federica FogacciHypertension and Atherosclerosis Research Group, Medical and Surgical Sciences Department; Sant'Orsola-Malpighi University Hospital, Building 2-IV Floor, Via Albertoni 15, 40138 Bologna, Italy.ORCID 0000-0001-7853-0042
Giovambattista DesideriDepartment of Life, Health and Environmental Sciences, University of L'Aquila, Coppito, 67100 L'Aquila, Italy.
Elisa GrandiHypertension and Atherosclerosis Research Group, Medical and Surgical Sciences Department; Sant'Orsola-Malpighi University Hospital, Building 2-IV Floor, Via Albertoni 15, 40138 Bologna, Italy.
Elisabetta RizzoliHypertension and Atherosclerosis Research Group, Medical and Surgical Sciences Department; Sant'Orsola-Malpighi University Hospital, Building 2-IV Floor, Via Albertoni 15, 40138 Bologna, Italy.
Sergio D'AddatoHypertension and Atherosclerosis Research Group, Medical and Surgical Sciences Department; Sant'Orsola-Malpighi University Hospital, Building 2-IV Floor, Via Albertoni 15, 40138 Bologna, Italy.ORCID 0000-0001-6631-4342
Claudio BorghiHypertension and Atherosclerosis Research Group, Medical and Surgical Sciences Department; Sant'Orsola-Malpighi University Hospital, Building 2-IV Floor, Via Albertoni 15, 40138 Bologna, Italy.
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITUniversity of L'Aquila · IT

Funding

Fondazione del Monte di Bologna e Ravenna FM2017
6 · The paper itself

Abstract

introductionThere is conflicting information linking fruit and fructose intake with cardiometabolic disorders. The main objective of our study was to evaluate the association between intake of fruits and sugar-sweetened beverages, and carotid-femoral pulse wave velocity (cfPWV), a non-invasive marker of arterial aging, in a large population sample.

methodsFor this study, we selected four age and sex-matched subgroups from the last Brisighella Heart Study population survey, after exclusion of those in secondary prevention for cardiovascular diseases, affected by gout and moderate-to-severe chronic kidney disease (defined as eGFR < 60 mL/min), and/or actively treated with direct vasodilating drugs (calcium-antagonists, alpha-blockers, nitrates). The remaining subjects were classified into four groups: (1) low fruit and low sugar-sweetened beverage intake (LFLB), (2) high fruit and low sugar-sweetened beverage intake (HFLB), (3) low fruit and high sugar-sweetened beverage intake (LFHB), (4) high fruit and high sugar-sweetened beverage intake (HFHB).

resultsCfPWV was significantly elevated in subjects consuming a higher fructose load, particularly when it was derived from industrially sweetened beverages (pooled LFHB & HFHB: 9.6 ± 2.3 m/s; pooled LFLB & HFLB: 8.6 ± 2.3 m/s,

conclusionour data suggest that increased intake of fructose derived from industrial sweetened beverages, though not from fruits, is associated with higher pulse wave velocity.

Indexed as

AdolescentAdultAgedAged, 80 and overBlood GlucoseCardiovascular DiseasesDietEatingFastingFemaleFructoseFruitGlomerular Filtration RateHumansItalyMaleBlood GlucoseFructoseTriglyceridesUric Acidarterial stiffnessfruitspulse wave velocityserum uric acidsugar-sweetened drinks

Identifiers

PMID31694231
PMCPMC6893603
OpenAlexW2989462543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.