Evidence map›Paper›PMID 31694207›Full record

ArticleViruses2019

Silent Circulation of the Saint Louis Encephalitis Virus among Humans and Equids, Southeast Brazil.

Galileu Barbosa Costa, Paula Eillany Silva Marinho, Ana Paula Pessoa Vilela, Ana Teresa Saraiva-Silva, Ana Paula Correia Crispim, Iara Apolinário Borges, Ana Gabriella Stoffella Dutra, Zélia Inês Portela Lobato, Jenner Karlison Pimenta Dos Reis, Danilo Bretas de Oliveira and 3 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Absence of yellow fever virus circulation in wildlife rodents from Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Article
  7. Article
  8. Viral Diseases that Affect Donkeys and Mules.Animals : an open access journal from MDPI · 2020
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Galileu Barbosa CostaLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais. Avenida Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte, Minas Gerais 31270901, Brasil.ORCID 0000-0001-7360-6722
Paula Eillany Silva MarinhoLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais. Avenida Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte, Minas Gerais 31270901, Brasil.
Ana Paula Pessoa VilelaLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais. Avenida Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte, Minas Gerais 31270901, Brasil.ORCID 0000-0001-9030-0688
Ana Teresa Saraiva-SilvaLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais. Avenida Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte, Minas Gerais 31270901, Brasil.ORCID 0000-0002-3782-2978
Ana Paula Correia CrispimLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais. Avenida Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte, Minas Gerais 31270901, Brasil.
Iara Apolinário BorgesLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais. Avenida Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte, Minas Gerais 31270901, Brasil.
Ana Gabriella Stoffella DutraLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais. Avenida Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte, Minas Gerais 31270901, Brasil.
Zélia Inês Portela LobatoLaboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270901, Brazil.
Jenner Karlison Pimenta Dos ReisLaboratório de Retroviroses, Departamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270901, Brazil.
Danilo Bretas de OliveiraFaculdade de Medicina, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina 39100000, Brazil.
Betania Paiva DrumondLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais. Avenida Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte, Minas Gerais 31270901, Brasil.
Erna Geessien KroonLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais. Avenida Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte, Minas Gerais 31270901, Brasil.ORCID 0000-0003-2721-3826
Giliane de Souza TrindadeLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais. Avenida Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte, Minas Gerais 31270901, Brasil.
Universidade Federal de Minas Gerais · BRUniversidade Federal dos Vales do Jequitinhonha e Mucuri · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saint Louis encephalitis virus (SLEV) is a mosquito-borne flavivirus that occurs throughout the Americas, and is considered a public health threat. In Brazil, SLEV has been detected from human cases associated with dengue-like disease, but no neurological symptoms were reported. Furthermore, the epidemiology of SLEV in human populations is still poorly explored in the country. We reported serological and molecular detection of SLEV in a healthy population of equids and humans from rural areas in Southeast Brazil. A plaque reduction neutralization test was applied, and neutralizing antibodies were detected in 11 individuals (4.6%) and 60 horses (21.5%). A qPCR targeting the 5'UTR region and reverse transcription-PCR (RT-PCR) targeting the non-structural protein (NS5) gene were performed and three individuals tested positive in both assays. Subsequent phylogenetic analysis confirmed SLEV circulation and its findings suggest the occurrence of an asymptomatic or subclinical presence in human and animal cases, correlating with the risks for outbreaks and consequently burden of SLEV infections to public health. Preventive strategies should include improved surveillance in regions with a high probability of SLEV occurrence, improvement in diagnostic methods, and evaluation of exposure/risk factors that can favor SLEV emergence.

Indexed as

Encephalitis, St. LouisEncephalitis Virus, St. LouisAnimalsAntibodies, NeutralizingAntibodies, ViralAsymptomatic InfectionsBrazilDengueDiagnosis, DifferentialFlaviviridaeGenes, ViralHorse DiseasesHorsesHumansNeutralization TestsPhylogenyAntibodies, NeutralizingAntibodies, Viralasymptomatic casesepidemiologypublic health burdenSaint Louis encephalitis virusseroprevalence

Identifiers

PMID31694207
PMCPMC6893452
OpenAlexW2983349130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.