ArticleMaterials (Basel, Switzerland)2019
Human Mesenchymal Stem Cell Combined with a New Strontium-Enriched Bioactive Glass: An
Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- SrO-Containing Bioactive Glasses in the SiOACS biomaterials science & engineering · 2025Review
- A Multidisciplinary Evaluation of Three-Dimensional Polycaprolactone Bioactive Glass Scaffolds for Bone Tissue Engineering Purposes.Materials (Basel, Switzerland) · 2024Article
- Recent Advance of Strontium Functionalized in Biomaterials for Bone Regeneration.Bioengineering (Basel, Switzerland) · 2023Review
- Bioactive Glasses in Periodontal Regeneration: Existing Strategies and Future Prospects-A Literature Review.Materials (Basel, Switzerland) · 2022Review
- Strontium Functionalization of Biomaterials for Bone Tissue Engineering Purposes: A Biological Point of View.Materials (Basel, Switzerland) · 2022Review
- A New Generation of Electrospun Fibers Containing Bioactive Glass Particles for Wound Healing.Materials (Basel, Switzerland) · 2020Article
- A Review of Bioactive Glass/Natural Polymer Composites: State of the Art.Materials (Basel, Switzerland) · 2020Review
- Effects of a Novel Bioactive Glass Composition on Biological Properties of Human Dental Pulp Stem Cells.Materials (Basel, Switzerland) · 2020Article
- Chitosan-Based Bioactive Glass Gauze: Microstructural Properties, In Vitro Bioactivity, and Biological Tests.Materials (Basel, Switzerland) · 2020Article
- On the in Vitro Biocompatibility Testing of Bioactive Glasses.Materials (Basel, Switzerland) · 2020Article
- Advances in the application of gold nanoparticles in bone tissue engineering.Journal of biological engineering · 2020Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 3D cellular model that mimics the potential clinical application of a biomaterial is here applied for the first time to a bioactive glass, in order to assess its biological potential. A recently developed bioactive glass (BGMS10), whose composition contained strontium and magnesium, was produced in the form of granules and fully investigated in terms of biocompatibility in vitro. Apart from standard biological characterization (Simulated Body Fluid (SBF) testing and biocompatibility as per ISO10993), human bone marrow mesenchymal stromal/stem cells (BM-MSCs) were used to investigate the performance of the bioactive glass granules in an innovative 3D cellular model. The results showed that BGMS10 supported human BM-MSCs adhesion, colonization, and bone differentiation. Thus, bioactive glass granules seem to drive osteogenic differentiation and thus look particularly promising for orthopedic applications, bone tissue engineering and regenerative medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.