Evidence map›Paper›PMID 31693977›Full record

ArticleRedox biology2020

Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H

Nuno Almeida, Guia Carrara, Carlos M Palmeira, Ana S Fernandes, Maddy Parsons, Geoffrey L Smith, Nuno Saraiva

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Redox biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. The Golgi CaBiophysics reports · 2024
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Frontiers in physiology · 2023
    Article
  8. Article
  9. Article
  10. LOXL2 Inhibitors and Breast Cancer Progression.Antioxidants (Basel, Switzerland) · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Nuno AlmeidaCBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies, Campo Grande 376, Lisbon, 1749-024, Portugal.
Guia CarraraDepartment of Pathology, University of Cambridge, Cambridge, CB2 1QP, UK.
Carlos M PalmeiraDepartment of Life Sciences, University of Coimbra, Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal.
Ana S FernandesCBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies, Campo Grande 376, Lisbon, 1749-024, Portugal.
Maddy ParsonsRandall Centre for Cell and Molecular Biophysics, King's College London, Guys Campus, London, SE1 1UL, UK.
Geoffrey L SmithDepartment of Pathology, University of Cambridge, Cambridge, CB2 1QP, UK.
Nuno SaraivaCBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies, Campo Grande 376, Lisbon, 1749-024, Portugal. Electronic address: nuno.saraiva@ulusofona.pt.
Universidade Lusófona · PTUniversity of Cambridge · GBKing's College London · GBUniversity of Coimbra · PT

Funding

Medical Research Council G0900224Wellcome Trust 090315/B/09
6 · The paper itself

Abstract

The mechanisms by which the Golgi apparatus (GA) impacts on cell invasion are poorly understood. The human Golgi Anti-Apoptotic Protein (hGAAP, also known as TMBIM4) is a highly conserved Golgi cation channel that modulates intracellular Ca

Indexed as

AnimalsCalcium SignalingCell AdhesionCell Line, TumorCell MovementCell SurvivalHumansHydrogen PeroxideMCF-7 CellsMembrane ProteinsMiceMitochondriaNeoplasm InvasivenessNeoplasmsNeoplasm TransplantationReactive Oxygen SpeciesHydrogen PeroxideMembrane ProteinsReactive Oxygen SpeciesTMBIM4 protein, humanCalciumCell invasionGolgi apparatusHydrogen peroxideMetabolismTMBIM

Identifiers

PMID31693977
PMCPMC6838802
OpenAlexW2981395802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.