ArticleCell reports2019
Hepatocytes Delete Regulatory T Cells by Enclysis, a CD4
Open access · goldAbstract read
In one paragraph
Article in Cell reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 48 citations in OpenAlex.
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- The role of immune regulation in HBV infection and hepatocellular carcinogenesis.Frontiers in immunology · 2025Review
- Implication of IZUMO2 in the cell-in-cell phenomenon: A potential therapeutic target for triple-negative breast cancer.Thoracic cancer · 2024Article
- Expression of E-cadherin by CD8Nature communications · 2024Article
- Adiponectin-expressing Treg-containing T cell fraction inhibits tumor growth in orthotopically implanted triple-negative breast cancer.Thoracic cancer · 2023Article
- Cell-in-Cell Structures in Gastrointestinal Tumors: Biological Relevance and Clinical Applications.Journal of personalized medicine · 2023Review
- Potential activity of adiponectin-expressing regulatory T cells against triple-negative breast cancer cells through the cell-in-cell phenomenon.Thoracic cancer · 2023Article
- Review
- Autoimmunity and Carcinogenesis: Their Relationship under the Umbrella of Autophagy.Biomedicines · 2023Review
- Tumor malignancy by genetic transfer between cells forming cell-in-cell structures.Cell death & disease · 2023Article
- AIM-CICs: an automatic identification method for cell-in-cell structures based on convolutional neural network.Journal of molecular cell biology · 2022Article
- Cell-in-cell structure mediates in-cell killing suppressed by CD44.Cell discovery · 2022Article
- Cell-in-Cell: From Cell Biology to Translational Medicine.BioMed research international · 2022Review
- Cell-in-Cell Events in Oral Squamous Cell Carcinoma.Frontiers in oncology · 2022Review
- Fine-tuning of regulatory T cells is indispensable for the metabolic steatosis-related hepatocellular carcinoma: A review.Frontiers in cell and developmental biology · 2022Review
- Hepatocytes: A key role in liver inflammation.Frontiers in immunology · 2022Review
- Review
- Characterization of epithelial cells, connective tissue cells and immune cells in human upper airway mucosa by immunofluorescence multichannel image cytometry: a pilot study.Histochemistry and cell biology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 5 institutions in 2 countries.
Scott P DaviesInstitute of Immunology and Immunotherapy, Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK.
Gary M ReynoldsInstitute of Immunology and Immunotherapy, Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK; NIHR Birmingham Liver Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Alex L WilkinsonInstitute of Immunology and Immunotherapy, Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK.
Xiaoyan LiInstitute of Immunology and Immunotherapy, Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK; Department of Infectious Diseases and Guangdong Provincial Key Laboratory of Liver Disease Research, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Rebecca RoseInstitute of Immunology and Immunotherapy, Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK.
Maanav LeekhaInstitute of Immunology and Immunotherapy, Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK.
Yuxin S LiuInstitute of Inflammation and Aging, University of Birmingham, Birmingham, UK.
Ratnam GandhiInstitute of Immunology and Immunotherapy, Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK.
Emma BuckroydInstitute of Immunology and Immunotherapy, Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK.
Joe GroveInstitute of Immunity and Transplantation, Division of Infection and Immunity, University College London, London, UK.
Nicholas M BarnesNeuropharmacology Research Group, Institute of Clinical Sciences, University of Birmingham, Birmingham, UK.
Robin C MayInstitute of Microbiology and Infection and School of Biosciences, University of Birmingham, Birmingham, UK.
Stefan G HubscherInstitute of Immunology and Immunotherapy, Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK; NIHR Birmingham Liver Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK; Department of Cellular Pathology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
David H AdamsInstitute of Immunology and Immunotherapy, Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK; NIHR Birmingham Liver Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Yuehua HuangDepartment of Infectious Diseases and Guangdong Provincial Key Laboratory of Liver Disease Research, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Omar QureshiCelentyx Ltd., Birmingham Research Park, Birmingham B15 2SQ, UK; Celentyx Ltd., BioEscalator Innovation Building, Oxford OX3 7FZ, UK.
Zania StamatakiInstitute of Immunology and Immunotherapy, Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK; NIHR Birmingham Liver Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK. Electronic address: z.stamataki@bham.ac.uk.
University of Birmingham · GBUniversity Hospitals Birmingham NHS Foundation Trust · GBSun Yat-sen University · CNBirmingham Research Park · GBUniversity College London · GB
Funding
Medical Research Council G0300101Medical Research Council G0300102Medical Research Council G0400496Medical Research Council G0700301Medical Research Council G0802577Medical Research Council MC_PC_14123Medical Research Council MR/M009157/1National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/R002061/1Wellcome Trust
Abstract
CD4
Indexed as
beta CateninCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell AdhesionCell LineEndocytosisEndosomesForkhead Transcription FactorsHepatocytesHumansImmune ToleranceIntercellular Adhesion Molecule-1LiverLysosomal-Associated Membrane Protein 1Lysosomal Membrane ProteinsLysosomesbeta CateninForkhead Transcription FactorsFOXP3 protein, humanICAM1 protein, humanIntercellular Adhesion Molecule-1LAMP1 protein, humanLysosomal-Associated Membrane Protein 1Lysosomal Membrane Proteinscell-in-cell structuresefferocytosisemperipolesisenclysisendocytosisentosishepatocytesliverT cellsβ-catenin
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.