Evidence map›Paper›PMID 31693205›Full record

ReviewJournal of neuroscience research2020

Neural substrates of habit.

Melissa Malvaez

Abstract readReview
In one paragraph

Review in Journal of neuroscience research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Goal-directed actions and habits in head-fixed mice.Frontiers in behavioral neuroscience · 2026
    Article
  4. Article
  5. Article
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  13. Medial septum activation improves strategy switching once strategies are well-learned via bidirectional regulation of dopamine neuron population activity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
  14. Review
  15. Review
  16. The Medial Orbitofrontal Cortex-Basolateral Amygdala Circuit Regulates the Influence of Reward Cues on Adaptive Behavior and Choice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Melissa MalvaezDepartment of Psychology, UCLA, Los Angeles, CA, USA.ORCID 0000-0002-3498-6678

Funding

UCLA Training Program in Translational Neuroscience of Drug Abuse (TNDA)T32DA024635 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LARA A. RAY, Kate M Wassum · 2008 to 2026
$6.2M
Basolateral Amygdala Rapid Glutamate Signaling During Reward Decision-MakingR01DA035443 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Kate M Wassum · 2013 to 2026
$5.7M
Epigenetic Regulation Of Striatal Circuit Function For Action And Habit LearningR01DA046679 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WASSUM, KATE M · 2019 to 2023
$2.7M
NIDA NIH HHS R01 DA035443NIDA NIH HHS R01 DA046679NIDA NIH HHS T32 DA024635
6 · The paper itself

Abstract

Active reward pursuit is supported by the balance between the cognitive and habitual control of behavior. The cognitive, goal-directed strategy relies on the prospective evaluation of anticipated consequences, which allows behavior to readily adapt when circumstances change. Repetition of successful actions promotes less cognitively taxing habits, in which behavior is automatically executed without prospective consideration. Disruption in either of these behavioral regulatory systems contributes to the symptoms that underlie many psychiatric disorders. Here, I review recently identified neural substrates, at multiple neural levels, that contribute to habits and outline gaps in knowledge that must be addressed to fully understand the neural mechanisms of behavioral control.

Indexed as

HabitsRewardAnimalsBrainHumansNeural PathwaysNeuronal Plasticitybehavioral controlepigeneticsgoal-directedhabitsHDAC3plasticitystriatum

Identifiers

PMID31693205
PMCPMC7183880

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.