Evidence map›Paper›PMID 31692945›Full record

ArticleMolecular and clinical oncology2019

Nutritional benefit of laparoscopic jejunostomy during neoadjuvant chemotherapy for obstructing esophageal cancer.

Ken Nagata, Hironori Tsujimoto, Hiromi Nagata, Manabu Harada, Nozomi Ito, Shinsuke Nomura, Hiroyuki Horiguchi, Shuichi Hiraki, Suefumi Aosasa, Kazuo Hase and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Ken NagataDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Hironori TsujimotoDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Hiromi NagataDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Manabu HaradaDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Nozomi ItoDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Shinsuke NomuraDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Hiroyuki HoriguchiDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Shuichi HirakiDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Suefumi AosasaDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Kazuo HaseDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Hideki UenoDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
National Defense Medical College · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neoadjuvant chemotherapy (NAC) confers a survival benefit in esophageal carcinoma, but it is difficult to perform in patients who cannot receive enteral feeding due to an esophageal obstruction. In the current study, the nutritional benefit of laparoscopic jejunostomy (Lap-J) was evaluated in patients with NAC for obstructing esophageal cancer. A total of 91 patients with esophageal cancer who received NAC between 2009 and 2017 were included in the present study. Lap-J was performed prior to NAC in 15 patients (16.5%) with an obstructing tumor. Patients with NAC without Lap-J were used as the control group (n=76). Nutritional parameters and surgical outcomes of the two groups were compared retrospectively. In the patients with Lap-J, 14 of the 15 patients (93.3%) did not experience any procedure-associated complications. No mortalities were associated with Lap-J. Significant decreases in total serum protein, albumin, hemoglobin concentrations and prognostic nutritional index (PNI) occurred following NAC in the control but not in the Lap-J group. Serum albumin and the improved modified Glasgow prognostic score increased significantly after NAC in the Lap-J group but not in the control group. In conclusion, perioperative nutritional support with Lap-J was safe and effective in patients with NAC for obstructing esophageal cancer.

Indexed as

enteral nutritionesophageal cancerlaparoscopic jejunostomyminimal invasive surgery

Identifiers

PMID31692945
PMCPMC6826271
OpenAlexW2981290099

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.