ArticleThe Pan African medical journal2019
Hepatitis B mother-to-child transmission in the Eastern Region of Ghana: a cross-sectional pilot study.
Article in The Pan African medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Implementation Approaches for Introducing and Overcoming Barriers to Hepatitis B Birth-Dose Vaccine in sub-Saharan Africa.Global health, science and practice · 2022Pooled it
- Prevalence and risk factors for hepatitis B virus infection among expectant mothers in Jirapa Municipality, Upper West Region, Ghana: a facility-based cross-sectional study.BMC public health · 2026Article
- Beliefs and Perceptions of Midwives on Prevention of Mother-to-Child Transmission of Hepatitis B in Selected Primary Health Care Facilities in Ghana.Journal of pregnancy · 2026Article
- Hepatitis B Infection in Outpatients and Pregnant Women Visiting a Mission Hospital in Ghana.Public health challenges · 2025Article
- Predictive model for neonatal HBV infection risk in infants of HBV-infected mothers in China: an observational study.Frontiers in public health · 2025Observational
- Burden of hepatitis B virus infection in pregnant women attending antenatal clinics in the southern Gabon.IJID regions · 2023Article
- A nationwide cross-sectional review of in-hospital hepatitis B virus testing and disease burden estimation in Ghana, 2016 - 2021.BMC public health · 2022Article
- Article
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHepatitis B is a major health concern in Ghana, where prevalence of the virus remains high and most chronic patients are infected during childhood or at birth. This study aimed to determine the prevalence and main factors associated with mother-to-child transmission of hepatitis B in the context of Ghana.
methodsIn this cross-sectional pilot study, we tested infants born to hepatitis B positive mothers at a hospital in the Eastern Region of Ghana to determine the prevalence of mother-to-child transmission. A questionnaire was completed by hepatitis B positive mothers to investigate the association between factors surrounding the birth of the child and whether transmission had occurred. These factors were analyzed independently using Fisher's exact test. To investigate the relationship between mother's age at the time of delivery and viral transmission, a univariate logistic regression analysis was performed.
resultsThe prevalence of mother-to-child transmission was 5.9%, with 51 hepatitis B positive mothers included in the study and three infants testing positive. A majority of infants received the standard hepatitis B vaccination schedule (96.1%) while two-thirds received the birth dose. There was no significant association observed between the clinical interventions reported in the study and mother-to-child transmission. No significant association was observed between the age of the mother at the time of delivery and viral transmission (OR: 1.077, 95% CI: 0.828 - 1.403, p = 0.58). Viral marker testing during pregnancy was absent in the population and could not be reliably assessed.
conclusionThere was a low prevalence of HBV mother-to-child transmission observed despite a clear absence of viral marker and viral load testing. It is recommended that viral profile analysis is performed for hepatitis B positive pregnancies to identify high risk cases.
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