Evidence map›Paper›PMID 31692453›Full record

ArticleAging2019

Baicalein attenuates OVA-induced allergic airway inflammation through the inhibition of the NF-κB signaling pathway.

Tingting Xu, Xiangting Ge, Chun Lu, Wei Dai, Hongjin Chen, Zhongxiang Xiao, Liqin Wu, Guang Liang, Songmin Ying, Yali Zhang and 1 more

Open access · greenAbstract read
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. An Updated Comprehensive Review of Plants and Herbal Compounds with Antiasthmatic Effect.Evidence-based complementary and alternative medicine : eCAM · 2024
    Review
  12. Article
  13. Investigation of the activity of baicalein towards Zika virus.BMC complementary medicine and therapies · 2023
    Article
  14. Review
  15. The Flavonoid Components ofCurrent topics in medicinal chemistry · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Tingting XuThe Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Xiangting GeThe Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Chun LuThe Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Wei DaiThe Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Hongjin ChenChemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Zhongxiang XiaoAffiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou, China.
Liqin WuThe Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Guang LiangChemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Songmin YingThe Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Yali ZhangChemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Yuanrong DaiThe Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Wenzhou Medical University · CNSecond Affiliated Hospital of Zhejiang University · CNSecond Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is a type of chronic lung inflammation with restrictions in effective therapy. NF-κB pathway activation has been suggested to play an important role in the pathogenesis of asthma. Baicalein, one of the major active flavonoids found in

Indexed as

AnimalsAntioxidantsAsthmaCell LineCollagenDrug Evaluation, PreclinicalFlavanonesImmunoglobulin EMiceMucusNF-kappa BNitric Oxide Synthase Type IIOvalbuminPhytotherapyPlant ExtractsScutellaria baicalensisAntioxidantsbaicaleinCollagenFlavanonesImmunoglobulin ENF-kappa BNitric Oxide Synthase Type IINos2 protein, mouseOvalbuminPlant ExtractsScutellaria baicalensis extractasthmaBaicaleininflammationiNOSNF-κB

Identifiers

PMID31692453
PMCPMC6874438
OpenAlexW2984257522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.