Evidence map›Paper›PMID 31691843›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

Simultaneous PET-MRI imaging of cerebral blood flow and glucose metabolism in the symptomatic unilateral internal carotid artery/middle cerebral artery steno-occlusive disease.

Bixiao Cui, Tianhao Zhang, Yan Ma, Zhongwei Chen, Jie Ma, Lei Ma, Liqun Jiao, Yun Zhou, Baoci Shan, Jie Lu

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Simultaneous multiple post-labelling delay ASL MRI and [European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Article
  4. Comparison of the Correlation Between Cerebral [Molecular imaging and biology · 2025
    Article
  5. Quantitative Cortex-Based Mapping With HybridCNS neuroscience & therapeutics · 2025
    Article
  6. Article
  7. Comparison ofEJNMMI research · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Feasibility ofEuropean radiology · 2023
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Bixiao CuiDepartment of Nuclear Medicine, Xuanwu Hospital Capital Medical University, Beijing, China.
Tianhao ZhangBeijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.
Yan MaDepartment of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing, China.
Zhongwei ChenGE Healthcare, Beijing, China.
Jie MaDepartment of Nuclear Medicine, Xuanwu Hospital Capital Medical University, Beijing, China.
Lei MaDepartment of Nuclear Medicine, Xuanwu Hospital Capital Medical University, Beijing, China.
Liqun JiaoDepartment of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing, China.
Yun ZhouMallinckrodt Institute of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Baoci ShanBeijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China. shanbc@ihep.ac.cn.
Jie LuDepartment of Nuclear Medicine, Xuanwu Hospital Capital Medical University, Beijing, China. imaginglu@hotmail.com.ORCID 0000-0003-0425-3921
Capital Medical University · CNCenter for Excellence in Brain Science and Intelligence Technology · CNChinese Academy of Sciences · CNWashington University in St. Louis · US

Funding

Beijing Municipal Administration of Hospitals' Ascent Plan DFL20180802National Natural Science Foundation of China 81671662
6 · The paper itself

Abstract

purposeCerebral blood flow (CBF) and glucose metabolism are important and significant factors in ischaemic cerebrovascular disease. The objective of this study was to use quantitative hybrid PET/MR to evaluate the effects of surgery treatment on the symptomatic unilateral internal carotid artery/middle cerebral artery steno-occlusive disease.

methodsFifteen patients diagnosed with ischaemic cerebrovascular disease were evaluated using a hybrid TOF PET/MR system (Signa, GE Healthcare). The CBF value measured by arterial spin labelling (ASL) and the standardized uptake value ratio (SUVR) measured by

resultsThe analysis primarily revealed that after bypass surgery, a statistically significant increase occurred in the CBF on the affected side (P < 0.01). The postprocedural SUVR was not significantly higher than the preprocedural SUVR (P > 0.05). However, the postprocedural AI values for CBF and SUVR were significantly lower after surgery than before surgery (P < 0.01). A significant correlation was found between the AI values for preoperative CBF and SUVR on the ipsilateral hemisphere (P < 0.01).

conclusionsThe present study demonstrates that a combination of ASL and

Indexed as

Carotid Artery, InternalCerebrovascular CirculationGlucoseIschemiaMiddle Cerebral ArteryAdultFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPositron-Emission TomographyGlucoseCerebral blood flowGlucose metabolismIschaemic cerebrovascular diseasePET/MRSuperficial temporal artery-middle cerebral artery bypass

Identifiers

PMID31691843
PMCPMC7248051
OpenAlexW2988349149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.