Evidence map›Paper›PMID 31691699›Full record

ArticleThe Analyst2019

Enzymatic reaction-based nanopore detection of zinc ions.

Golbarg Mohammadi Roozbahani, Youwen Zhang, Xiaohan Chen, Mona Hoseini Soflaee, Xiyun Guan

Open access · greenAbstract read
In one paragraph

Article in The Analyst, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

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  9. Probe-assisted detection of FeBiosensors & bioelectronics · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Golbarg Mohammadi RoozbahaniIllinois Institute of Technology, 10 W 35th St, Chicago, Illinois 60616, USA. xguan5@iit.edu.
Youwen Zhang
Xiaohan Chen
Mona Hoseini Soflaee
Xiyun Guan
Illinois Institute of Technology · USUniversity of Illinois Chicago · US

Funding

Label-Free Nanopore Biosensor for Rapid, Ultrasensitive, and Multiplex Detection of Protease ActivitiesR15GM110632 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI GUAN, XIYUN · 2014 to 2017
$746k
NIGMS NIH HHS R15 GM110632
6 · The paper itself

Abstract

We report a label-free nanopore sensor for the detection of Zn2+ ions. By taking advantage of the cleavage of a substrate peptide by zinc-dependent enzymes, nanomolar concentrations of Zn2+ ions could be detected within minutes. Furthermore, structurally similar transition metals such as Ni2+, Co2+, Hg2+, Cu2+, and Cd2+ did not interfere with their detection. The enzymatic reaction-based nanopore sensing strategy developed in this work may find potential applications in environmental monitoring and medical diagnosis.

Identifiers

PMID31691699
PMCPMC7341991
OpenAlexW2980995191

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.