ArticleVeterinary medicine and science2020
Effect of dietary tryptophan supplementation on growth performance, immune response and anti-oxidant status of broiler chickens from 7 to 21 days.
Article in Veterinary medicine and science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Chicken IDO2 and TDO2: Biochemical Characteristics and Regulatory Roles in Avian Tryptophan Metabolism and Inflammatory Response.Animals : an open access journal from MDPI · 2026Article
- The dynamic requirements of tryptophan in the broilers at different growing stages under low-protein diets.Poultry science · 2026Article
- Amino Acid Nutrition in Poultry: A Review.Animals : an open access journal from MDPI · 2025Review
- Effect of Tryptophan Supplementation Levels on the Cecal Microbial Composition, Growth Performance, Immune Function and Antioxidant Capacity in Broilers.Metabolites · 2025Article
- Using a Multi-Attribute Decision-Making Method to Evaluate the Effect of in Ovo Injection of Valine and Tryptophan on the Growth Performance of Broiler Chickens.Veterinary medicine and science · 2025Article
- Untargeted metabolomics analysis of the spleens of ducks infected with Clostridium perfringens type A.BMC veterinary research · 2025Article
- Gut-X Axis and Its Role in Poultry Bone Health: A Review.Microorganisms · 2025Review
- Effects of Tryptophan Supplementation in Diets with Different Protein Levels on the Production Performance of Broilers.Animals : an open access journal from MDPI · 2024Article
- The Impact of Essential Amino Acids on the Gut Microbiota of Broiler Chickens.Microorganisms · 2024Review
- Ceruloplasmin Interferes with the Assessment of Blood Lipid Hydroperoxide Content in Small Ruminants.Antioxidants (Basel, Switzerland) · 2023Article
- Tryptophan oxidation in young children with environmental enteric dysfunction classified by the lactulose rhamnose ratio.The American journal of clinical nutrition · 2022Article
- Effects of dietary tryptophan supplementation on body temperature, hormone, and cytokine levels in broilers exposed to acute heat stress.Tropical animal health and production · 2022Article
- Tryptophan Alleviates Acute Heat Stress-Induced Impairment of Antioxidant Status and Mitochondrial Function in Broilers.Frontiers in veterinary science · 2022Article
- Systematic Review of the Interaction between Nutrition and Immunity in Livestock: Effect of Dietary Supplementation with Synthetic Amino Acids.Animals : an open access journal from MDPI · 2021Review
- Immunomodulatory, behavioral, and nutritional response of tryptophan application on poultry.Veterinary world · 2021Review
- Article
- Amino Acid Nutrition and Metabolism in Chickens.Advances in experimental medicine and biology · 2021Article
- Effect of dietary tryptophan supplementation on growth performance, immune response and anti-oxidant status of broiler chickens from 7 to 21 days.Veterinary medicine and science · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study was conducted to investigate the optimum dietary level of tryptophan (Trp) supplementation at which broiler chickens have better growth with efficient immune system and anti-oxidant status.
methodOne hundred and twenty (n = 120) 1-day-old broiler chicks were fed a common commercial diet from days 1 to 7. On day 7, the chicks were randomly divided in three treatment groups, that is, Trp 0.2 [national research council (NRC) recommended level of tryptophan], Trp 0.3 (tryptophan supplemented at 0.3%) and Trp 0.5 (tryptophan supplemented at 0.5%). All the experimental diets were iso-caloric (ME; 3,000 kcal/kg) and iso-proteic (CP; 18.5%). Weekly data on feed intake and body weight gain (BWG) were recorded to calculate feed conversion ratio (FCR). On day 19, avian tuberculin was injected to note the cellular immunity. On day 21, two birds per replicate were killed to determine carcass and visceral organ weights. Blood serum samples were collected for analysis of humoral immune response against sheep red blood cells, total oxidant and anti-oxidants by spectrophotometric method.
resultsFeed intake, carcass and visceral organ weights remained unaffected by dietary treatments while BWG and FCR tended to improve (p < .05) in broiler chicks fed the Trp 0.3 and the Trp 0.5 diets. Total oxidant status was also improved (p < .05) in broiler chicks fed the Trp 0.5 diet. Likewise, broiler chicks fed the Trp 0.3 and the Trp 0.5 diets tended to have better (p < .05) total anti-oxidant status, catalase, glutathione peroxidase, glutathione reductase and arylesterase (ARE). The overall antibodies response and IgG improved (p < .05) by the Trp 0.3 and Trp 0.5 diets compared to control. However, IgM level remained similar across the treatment. The cellular immunity against avian tuberculin improved at 24 hr post-injection but its effect disappeared at 48 hr.
conclusionThe results of present study revealed that Trp above the NRC recommended level may give better growth, immune response and anti-oxidant status in broiler chickens.
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