Evidence map›Paper›PMID 31691124›Full record

ArticleMikrochimica acta2019

Manganese(II)-doped carbon dots as effective oxidase mimics for sensitive colorimetric determination of ascorbic acid.

Shujuan Zhuo, Jing Fang, Meng Li, Jing Wang, Changqing Zhu, Jinyan Du

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 76 citations in OpenAlex.

  1. Preparation and Application of Carbon Dots Nanozymes.Antioxidants (Basel, Switzerland) · 2024
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. MnFrontiers in bioengineering and biotechnology · 2022
    Article
  9. Article
  10. Review
  11. Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shujuan ZhuoAnhui Laboratory of Molecule-Based Materials; Key Laboratory of Functional Molecular Solids, Ministry of Education; Anhui Key Laboratory of Chemo-Biosensing, School of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241000, People's Republic of China. sjzhuo@mail.ahnu.edu.cn.ORCID 0000-0003-3764-1496
Jing FangAnhui Laboratory of Molecule-Based Materials; Key Laboratory of Functional Molecular Solids, Ministry of Education; Anhui Key Laboratory of Chemo-Biosensing, School of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241000, People's Republic of China.
Meng LiAnhui Laboratory of Molecule-Based Materials; Key Laboratory of Functional Molecular Solids, Ministry of Education; Anhui Key Laboratory of Chemo-Biosensing, School of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241000, People's Republic of China.
Jing WangAnhui Laboratory of Molecule-Based Materials; Key Laboratory of Functional Molecular Solids, Ministry of Education; Anhui Key Laboratory of Chemo-Biosensing, School of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241000, People's Republic of China.
Changqing ZhuAnhui Laboratory of Molecule-Based Materials; Key Laboratory of Functional Molecular Solids, Ministry of Education; Anhui Key Laboratory of Chemo-Biosensing, School of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241000, People's Republic of China. zhucq@mail.ahnu.edu.cn.
Jinyan DuAnhui Laboratory of Molecule-Based Materials; Key Laboratory of Functional Molecular Solids, Ministry of Education; Anhui Key Laboratory of Chemo-Biosensing, School of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241000, People's Republic of China.
Ministry of Education of the People's Republic of China · CNAnhui Jianzhu University · CN

Funding

Anhui Laboratory of Molecule-Based Materials Open Fund fzj19006National Natural Science Foundation of China 21303003National Natural Science Foundation of China 21375003National Natural Science Foundation of China 21705003
6 · The paper itself

Abstract

A colorimetric assay is presented for the determination of ascorbic acid (AA). Manganese(II) doped carbon dots (Mn-CDs) were prepared by a convenient hydrothermal route and are shown to possess oxidase-like catalytic ability. They catalyze the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) by dissolved oxygen to form a blue colored product (oxTMB). AA can reduce blue oxTMB to colorless TMB. The fading of the blue color (measured at 652 nm) can be applied for quantifying AA in the 50 to 2500 nM concentration range and with a 9 nM detection limit. The method was successfully used for the quantitation of AA in real samples. Graphical abstract Schematic representation of a colorimetric assay platform for the sensitive detection of ascorbic acid (AA) in view of inhibitory effect of AA on the 3,3',5,5'-tetramethylbenzidine (TMB) oxidation, benefitting from excellent oxidase-like catalytic activity of manganese(II) doped carbon dots (Mn-CDs).

Indexed as

Ascorbic AcidBenzidinesCarbonCatalysisCitrus sinensisColorimetryColoring AgentsFruit and Vegetable JuicesHumansLimit of DetectionManganeseOxidation-ReductionOxidoreductasesQuantum DotsTablets3,3',5,5'-tetramethylbenzidineAscorbic AcidBenzidinesCarbonColoring AgentsManganeseOxidoreductasesTabletsAscorbic acid assayBlood serumColorimetryEnzyme mimeticInhibitory effectMetal dopingNanozymeOptical sensorOxidase-like activityTetramethylbenzidine

Identifiers

PMID31691124
OpenAlexW2986754641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.